Acidity of blood

Carbonic anhydrase regulates the acidity of blood and the physiological conditions relating to blood pH. 

Soupart, P., Free amino acids of blood and urine in the human. In Amino Acid Pools (J. T. Holden, ed.), pp. 220-263. Elsevier, Amsterdam, 1962. 

Gas chromatography, which has been applied to the separation of the tricarboxylic acid cycle acids in the liver (F8), might prove useful in the future in the field of organic acids of blood and urine. 

As important losses of a-keto acids occur during paper chromatography of organic acids (as free acids) of blood and urine, special techniques are used for these acids they include the preliminary transformation of the keto acids into more stable derivatives. 

Succinic Acid. Succinic acid was first detected in human blood serum by Thunberg (T20) its concentration is about 0.5-0.7 mg% (K14, T20). Its spot is generally found on chromatograms of organic acids of blood plasma (N19) (Fig. 2). It was also found in... 

Malic Acid. Malic acid appears regularly on chromatograms of organic acids of blood (N19) and urine (N20, 05). It can be determined quantitatively by the fluorimetric technique of Hummel (H31), who found values between 0.24 and 0.75 mg% in human whole blood. Much lower values (0.05-0.2 mg%) were found later with the same technique in dog blood plasma (V3). 

SI. Sabry, J. H., and Dodds, M. L., Comparative measurements of ascorbic acid and total ascorbic acid of blood plasma. J. Nutrition 64, 467-473 (1958). 

The examination of the students learning was based on a range of questions (approximately 50-60 per semester) that were dealt with in their tutorial groups - for example Explain how the acidity of blood is affected by respiration, a) in the lungs and b) in the body. These questions would then form the final examination of students in this course, This form of assessment was quite deliberate and consistent with Barry s purpose for the course as being to educate these students in appropriate fundamental chemical ideas, and not just train them for a particular vocation. ... 

The respiratory system helps control the acidity of blood by regulating the elimination of carbon dioxide and water molecules. These molecules, exhaled in every breath, come from carbonic acid as follows (see Figure 15.5) ... 

Martinelli, M., and Ghironzi, G. C. The Fatty Acids of Blood and Fecal... 

The Component Fatty Acids of Blood Fette, Seifen, Anstrichmittel 62 673-679 (1960) CA 55 2836a... 

Vanadium, Intracellular Acidity of Blood Cells, and Peptide Ligands... 

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