4-acetyl-2-hexyl

Primary+secondary removal benzyl acetate=86.4-99.9 methyl salicylate=92.0-99.9 methyl dihydrojasmonate=81.9-99.9 terpineol=95.4-99.9 benzyl salicylate=90.3-99.9 isobornyl acetate=84.5-99.9 g-methyl ionone=83.1-99.8 p-f-bucinal=84.8-99.3 hexylcinnamaldehyde=95.3-99.9 hexyl salicylate=96.4-99.9 OTNE=51.4-99.4 acetyl cedrene=71.3-99.9... 

Similarly, acetylation of thieno[3,2-6]thiophene (2) afforded 2-acetyl-thieno[3,2-6]thiophene, which was converted into methyl n-hexyl ketone by desulfurization with Raney nickel. Oxidation of 2-acetylthieno-[3,2-i]thiophene followed by nitration gave 5-nitrothieno[3,2-6]-thiophene-2-carboxylic acid. Decarboxylation of the latter furnished 2-nitrothieno[3,2-ft]thiophene identical with the compound obtained by direct nitration of thienothiophene 2 [Eq. (60)]. 

The reactivity of the carbonyl group in a,/3-unsaturated dialdoses was studied in more detail. The interaction with phenylhydrazine and its derivatives led to different results. 3-0-Benzyl-l,2-0-cyclo-hexyl idene-5,6-dideoxy-a-D-xyZo-hept-5-e nodialdo-l,4-furanose (56) gave57 a (2,4-dinitrophenyl)hydrazone. Action of (2,4-dinitrophenyl)-hydrazine on derivatives 67 led18 to complex mixtures. In the case of the acetylated derivatives (66), as well as of branched-chain derivatives (69), the interaction with (2,4-dinitrophenyl)hydrazine resulted in the formation of the expected hydrazones (Refs. 24 and 51, respectively). The interaction with phenylhydrazine was, however, proved to proceed by two paths in this case. Only the nitro derivatives (66, R = p-nitrophenyl) and (69, R = p-nitrophenyl) were shown24,51 to form the expected hydrazones. The phenyl derivative 66 (D-galacto, R = Ph) and p-methoxyphenyl derivative 69 (R = p-MeOC8H4) afforded substituted pyrazolines (74) (Ref. 24) and (75) (Ref. 51), respectively, as a result of subsequent intramolecular addition of a... 

Acetyl- VII/2a, 32 l-Oxa-spiro[2.2[pentan 2-Hexyl-2-methyl- E17b, 1308 (l-Br-2-OH -> Oxiran)... 

Acetyl-5-hexyl-2-methyl-4,5-dihydro- E19a, 630 [Keton +... 

During the search for homogeneous systems in which the tetravalent perhalotellurium compounds would undergo addition to an alkene, trimethylchlorosilane, acetyl chloride, or acetyl bromide were found to be a convenient source of halogens for the conversion of tellurium dioxide to a tellurium tetrahalide88. Addition of twice the stoichiometrically required amount of cyclohexene to a solution of tellurium tetrahalide, thus generated in either acetic acid, dichloromethane or ethanol-free chloroform leads to the formation of (fra i-2-halocyclo-hexyl)tellurium trihalides in ca. 70% yield. When dry methanol is used as solvent, trans-2-... 

Fosinopril Sodium. Fosinopril sodium. (4,S)-4-cyclo-hexyl-1 -I I l(/fS)-1 -hydroxy-2-methylpropoxy (4-phenyl-bu-(yl)phosphinyl acetyl -(.-proline sexlium salt (Monopril). is a phosphorus-containing ACE inhibitor. It is inactive but. serves us a prodrug. being completely hydrolyzed by intestinal and liver en/ymes to (he active diacid fosinoprilat. 

The a proton of a substituted cyclopropane is also rendered acidic if the substituent is attached to the ring by C-P bonds. A few reports have appeared on a-substitution in such compounds.(Cyclopropyl)triphenylphosphonium bromide was converted to a (1-ethoxy-carbonylcyclopropyl)triphenylphosphonium salt 18 in 80% yield by sequential treatment with lithium diisopropylamide and ethyl chloroformate. Furthermore, some diethyl cyclopropyl-phosphonates were converted, in some cases in excellent yield, to diethyl (1-hydroxymethyl-cyclopropyl)phosphonates by treatment with lithium diisopropylamide followed by addition of an aldehyde." Thus, typically, diethyl 2-hexylcyclopropylphosphonate gave diethyl 2-hexyl-l-[hydroxy(phenyl)methyl] cyclopropylphosphonate (19b) in 90% yield on reaction with benzaldehyde. ° Other electrophiles such as acetone, acetyl chloride, acetic anhydride, and ethyl acetate, were not sufficiently reactive to undergo addition to the anion. 

Acetyl-l,2-dibutyl- 119 (2-Hexyl-3-hydroxy-butylidene)- 1374 1 -(1 -Hydroxy-ethyl)-1 -(1 -octenyl)-... 

Abbreviations Ac acetyl Bn benzyl Cu(OTf)2 copper triflate Et ethyl HOTf trifluoromethanesulfonic acid KHMDS potassium hexamethyldisilazane Kim potassium imidazole / Hx / Hexyl Me methyl ... 

Hexyl Jasmat . [BASF AG] Acetyl eAyl octanoate floral, herbel, green, jasmine-like fragrance. 

The following abbreviations have been used for substituents Me = methyl Et = ethyl Pr = propyl Bu = butyl Pent = pentyl Hex = hexyl Oct = octyl Ph = phenyl Ac = acetyl apio/ = apio-furanoside galp = galacto-pyranoside glcp = gluco-pyranoside rhamps rhamno-pyranosyl, xylp = xylo-pyranosyl. 

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