Acetyl Chloride enol acetylation

Enol acetates are readily prepared from saturated ketones by reaction with acetic anhydride alone or diluted, in the presence of acetyl chloride ... 

Enol esterification with acetyl chloride-acetic anhydride gives the A -trien-3-acetate, but reaction with isopropenyl acetate or with hot acetic anhydride-pyridine gives A " -trien-3-acetates. " Since A"" -3-ketones react with Girard reagents, these linear dienones can be separated from A ""-3-ketones. ... 

The most simple l, 4-dithiocin system, which is stable, is the 6-acetoxy derivative 13, which can be synthesized from 1,4-dithiocin-6(57/)-onc (12) by trapping its enolate with acetyl chloride.7 9... 

High antiscorbutic power is also reported to be shown by a derivative of L-ascorbic acid in which the enolic hydroxyl group at C2 is replaced by an amino group. 3,4-Isopropylidene-L-threonic acid (LX), prepared from 5,6-isopropylidene-L-ascorbic acid, is converted into the 2-acetyl-3,4-isopropylidene-L-threonyl chloride (LXI) and this is then allowed to react with the sodium derivative of ethyl malonate. 

Many examples exist where the open chain betaine may be quenched by reagents, giving stable phosphorus compounds with P-C1V = 3. When (180) is reacted with acetyl chloride the open chain enol phosphate (181) is formed. Many interesting O- and N-phosphaspirans are also mentioned in (75BSF407). 

Diketones are converted into pyranones on treatment with malonyl dichloride, involving both C- and O-acylation (63JCS4483). The reaction between benzoylacetone and the acid chloride gives only one pyranone in accordance with a preferred direction of enolization consequent upon the unsymmetrical nature of the diketone a 5-acetyl-6-phenylpyranone results rather than the 5-benzoyl-6-methyl isomer. There is still some uncertainty as to whether the product is the 4-hydroxypyran-2-one (409) or the tautomer, but the former is considered to be the more likely. There is yet further controversy, since... 

N-Acetyl-L-phenylalanylsarcosine amide, 348 O-Acetylserine, 148 N-0 Acyl migrations, 157 Acyl-enzyme, 342-350 Z-0-Acylisoamide, 295 1,4-Addition, 221-242 1,6-Addition, 231 L-Ala-L-Ala-pNA,350 f-Ala-T-Pro-pNA, 350 AicohoT dehydrogenase, 340-341 Aldehydes, 209-211 Aldol condensation, 304-306 2-Alkoxytetrahydrofuran, 86 2-Alkoxytetrahydropyran, 18, 85-90 Alkylation of enamine, 282 Alkylation of enolate, 280 C and 0-Alkylation, 240 O-Alkylbenzohydroximoyl chloride, 155... 

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