Pentoxifylline Acenocoumarol

Some studies have suggested that pentoxifyllme does not alter the anticoagulant effects of phenprocoumon or acenocoumarol however, one study suggests that there is an increased risk of serious bleeding if pentoxifylline is given with acenocoumaroL Pentoxifylline alone has rarefy been associated with bleeding. 

PENTOXIFYLLINE ANTICOAGULANTS-ORAL Case reports of major haemorrhage when pentoxifylline was given with acenocoumarol Uncertain possibly additive effect (pentoxifylline has an antiplatelet action) Monitor INR closely... 

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