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Absorption - in-vitro Tests - Non-Cell Based

3 Parallel Artificial Membrane Permeability Assay (PAMPA). . 468 [Pg.461]

Several in vitro assays using filter immobilized artificial membranes exist for the estimation of permeability (Parallel artificial membrane permeation assay, PAMPA). In these assays the permeation of a compound is followed directly by estimating the amount of compound on either side of the membrane barrier. The results of these experiments are expressed as permeability values rather than lipophilicity values. [Pg.461]

A number of review articles and books described recently the methods used in pharmaceutical research to early on estimate the absorption potential of a compound by means of a variety of techniques. [Pg.461]

Kramer SD (1999) Absorption prediction from physicochemical parameters. PSTT 2 373-380 [Pg.461]

Kramer SD, Folkers G, Testa B (eds) (2004) Physicochemical and biological profiling in drug research. Wiley-VCH, Weinheim (presentations at LogP 2004 conference in Zurich) [Pg.461]

Chapter II.E Absorption - in-vitro Tests - Non-Cell Based... [Pg.462]

See other pages where Absorption - in-vitro Tests - Non-Cell Based is mentioned: [Pg.461]    [Pg.461]    [Pg.159]    [Pg.281]   


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