Absorption comparison

Figure 5.29 Special-type multi-purpose micro devices and mixing tee used for investigation of CO2 absorption. Comparison of their reactor performance as a function of the residence time. Micro bubble columns ( ) 1100 pm x 170 pm, (A) 300 pm x 100 pm and (T) 50 pm x 50 pm Interdigital mixer ( ) (40 pm) caterpillar mixer (A) (850 pm ramp) mixing tee (0) (1 mm) [5],...

Palm, K., Luthman, K., Ungell, A.-L., Strandlund, G., Beigi, F., Lundahl, P., Artursson, P. Evaluation of dynamic polar molecular surface area as predictor of drug absorption comparison with other computational and experimental predictors. J. Med. Chem. 1998, 41, 5382-5392. 

C. G. Gray, B. G. Nickel, J. D. Poll, S. Singh, and S. Weiss. Line shape in collision induced absorption comparison of theory and computer simulation. Molec. Phys., 58 253, 1986. 

Heinemann, T., Kullak-Ublick, G.-K., Pietruck, B., and von Bergmann, K. 1991. Mechanisms of action of plant sterols on inhibition of cholesterol absorption. Comparison of sitosterol and sitostanol. Eur. J. Clin. Pharmacol. 40, S50-S63. 

Pharmacokinetics and absorption of the drug should be linear. If the pharmacokinetic processes are dependent on the fraction of dose reaching the systemic blood flow (or of the dose administered) or on the rate of absorption, comparison between formulation and simulation cannot be made. This non-linearity may be owing to saturable absorption processes (active absorption), induction or inhibition of the metabolism, the first past effect, which is rate/absorption dependent, etc. Those points must be studied before any attempt to establish an IVIVC. 

Blumsohn A, Morris B, Eastell R. Stable strontium absorption as a measure of intestinal calcium absorption comparison with the double-radiotracer calcium absorption test. Clin Science 1994 87 363-368. 

RA Conradi, KF Wilkinson, BD Rush, AR Hilgers, MJ Ruwart, PS Burton. In vitro/in vivo models for peptide oral absorption comparison of Caco-2 cell permeability with rat intestinal absorption of renin inhibitory peptides. Pharm Res 10 1710-1714, 1993. 

Palm K, Luthman K, Ungell AL, Strandlund G, Beigi F, Lundahl P, and Artursson P. Evaluation of Dynamic Polar Molecular Surface Area as Predictor of Drug Absorption Comparison with Other Computational and Experimental Predictors./Med Chem 1998 41 5382-5392. 

Ogihara T, Kamiya M, Ozawa M, Fujita T, Yamamoto A, Yamashita S, Ohnishi S, Isomura Y. What kinds of substrates show P-glycoprotein-dependent intestinal absorption Comparison of verapamil with vinblastine. Drug Metab Pharmacokinet 2006 21 238-244. 

Table 3 Moisture Vapor Transmission vs. Moisture Absorption Comparison... 

Figure 14. Absorption comparison of 4T, 5T, 6T. All spectra are displayed with respect to the given energies, to emphasize the analogy within the fine structures. The positions of the vibrational modes are indicated and the first three fundamental modes are labelled (Table 1).

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