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Absorption compact solids

The physical properties of the drag substance and excipients are important in the manufacture, packaging, shipping, and use of drags [1]. These physical properties include solubility, dissolution rate, stability, particle size, water absorption, compactibility, and others. The crystalline form of the solid affects each of these properties. The physical form (i.e. polymorphism) of the drag substance can even affect the bioavailability of the drag and its effectiveness as a medicine [2]. Different solid-state forms of a chemical can be patented, thereby protecting the intellectual property of the pharmaceutical company, which can have a... [Pg.295]

In our opinion, the use of and calculations for one-particle Green s functions are uniquely suitable for solid-state systems periodic in any number of dimensions. When faithfully implemented, it satisfies all criteria above. Green s functions offer analytically compact and physically rich tools for representing many properties for extended, periodic systems. They satisfy powerful and elegant relations for quantities such as density of states, lifetimes for excitations, dielectric functions, photo-emission and absorption spectra, total crystal energies, and many more. [Pg.38]

SEA mixes also exhibited good resistance to water absorption and lower air void contents. The former is attributed to the added presence of the solid sulfur and the latter is achieved by virtue of higher degrees of compaction possible with the lower viscosity SEA binders. [Pg.173]

When the medium is not a dilute solution, but a concentrated solution, a colloid, a semisolid, or a solid made of compacted particles, the absorption of the light deviates from Beer s law. Beer s law assumes that when a photon encounters an absorbing particle, it will be either absorbed or transmitted. However, light-particle interaction can also generate a scattering event (forward or backward scatter) when not reflected. In a particulate sample, multiple scattering events can occur, thus generating a... [Pg.10]

In addition the irreversible shrinkage intensity depends on the chemical nature of the solid surface. IR measurements performed before and after compaction clearly indicate that this densification is related to a condensation reaction of silanols and an associated creation of water. A sharp increase in the IR absorption band located at 1620 cm corresponding to deformation vibration of free water has indeed been evidenced (Duffours, 1996). [Pg.1284]


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See also in sourсe #XX -- [ Pg.152 ]




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Compact Solids

Solids compaction

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