Ziprasidone nausea

Ziprasidone is well tolerated. Its common side effects are drowsiness, nausea, and constipation. Though there were initial concerns about untoward cardiological side effects similar to those produced by thioridazine and the tricyclic antidepressants, ziprasidone appears to be safe though it should probably not be used in patients with preexisting heart disease. 

The most common side effects are headache, dyspepsia, nausea, constipation, abdominal pain, somnolence, and EPS. Ratings of parkinsonism and akathisia with ziprasidone, 120 mg/day, did not differ from those with placebo. Although dizziness has been reported, rates of orthostatic hypotension have not differed from rates associated with placebo in controlled clinical trials. 

Published and unpublished studies from 1995 to 2004, in which intramuscular ziprasidone was assessed, have been reviewed (9). The most common adverse events in the 921 patients were nausea, headache, dizziness, anxiety, somnolence, insomnia, and injection-site pain 1.1 to 6.1% withdrew because of treatment-related adverse events. 

Ziprasidone 10-20 mg twice daily may titrate every Nausea, restlessness, insomnia. 

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