X-Anilino

X-anilino)-pent-3-en-2-ones in sulphuric acid at 25 °C377... 

K-AniUno-butyrophenon 14, 65. x-Anilino-i )bat TOphenoD 14, 66. 4-[a-Anilino-propionyl]-toluoI 14, 66. ms-Dimethylamlno-deaoxybenzoin 14 I 395. 4-DlmethyUiiiino.3-methyl-benzophenon... 

Series 2-amino-4-anilino-6-chloro-s-triazine k in liter x mole x sec . Ref. 49. Series 2-substituted-4,6-dichloro-s-triazine k in hr i. Ref. 39. 

Morpholino-3-[4-phenyl(thiosemicarbazido)carbonyl]quinoxaline (129) gave 2-morpholino-3-(4-phenyl-5-thioxo-5,6-drhydro-4//-l,2,4-triazol-3-yl)quin-oxaline (130) (2M NaOH, reflux, 3 h 35%), 2-(5-anilino-l,3,4-thiadiazol-2-yl)-3-morpholinoquinoxaline (131, X = S) (98% H2SO4, 0°C, 1 h, then 20°C, 12 h 89%), or 2-(5-anilino-l,3,4-oxadiazol-2-yl)-3-morpholinoquinoxaline (131, X = O) (NaOH, H2O, EtOH, I/Kii dropwise, 5°C 95°C, 4 h 81%) analogs of all three products were made similarly. ... 

Tetrahydrofuran moiety of 2 -anilino-6 -(iV-ethyl-/V-tetrahydrofurfur-ylamino)-3 -methylfluoran (91) can be hydrolyzed with 48% hydrobromic acid in sulfolane to give 2 -amli no-6 -[Af-(5-bromo-2-hydroxypentyl)-N-ethylamino]-3 -methylfluoran (92 X = OH)72 and 2 -ani lino-6 -[/V-(2,5-di-bromopentylj-/V-ethylamino]-3 -methylfluoran (92 X = Br)72 at 70-90 °C and 100 °C, respectively (Eq. 11). 

The effects of the 1,2,3-triazole and 1-amino-1,2,3-triazole heterocycles on the chemical shift of the carbon atoms in the phenyl ring of compounds (40) and (41) (X = H) are compared with the value for benzene. With regard to the effects of substituent X para and meta) on the 1,2,3-triazole carbons, C(4) is deshielded by electron-withdrawing groups, whereas C(5) is shielded. Reasonable correlations with Hammett a values are observed for the chemical shifts of both C(4) and C(5) of (41) <86MRC53>. The chemical shifts of C(4) and C(5) in 5-amino-l-aryl-l,2,3-triazoles are shifted upheld by 2-5 ppm compared with the corresponding 5-anilino-1,2,3-triazoles. In 5-anilino-... 

The A-acetyl derivatives of the 2-alkylthio-l,3-thiadiazol-4-imines (124, R = SR, R = Ac) undergo nucleophilic displacement reaction with amines (benzylamine, cyclohexylamine, morpholine, or aniline) giving the 2-amino derivatives (124, R = NRj, R = Ac). The salt (126, R = R = Ph, R = R = H, X = Cl) reacts with aniline at room temperature giving 4-anilino-2-phenyl-l,3-thiazole (128), presumably by a mechanism involving cleavage of the heterocyclic ring. ... 

Aus Anilino-guanidin werden mit a -Brom-acetophenonen 4-Aryl-2-(2-phenyl-hydrazino)-imidazole und nicht die ebenfalls als Produkte denkbaren 2-Amino-l-anilino-imidazole erhalten106 (s.a. Bd.X/2, S. 739) ... 

So erhalt man z.B. aus Azido-benzol und Benzol (X = H) ein Gemisch von (2-Amino-phenyl) -phenyl-amin (73%), 2-Amino- (8%) und 4-Amino-biphenyl (8%). Wahrend in ana-logen Fallen ahnliche Gemische entstehen, erhalt man unter gleichen Bedingungen aus Azidobenzol und Naphthalin 1-Anilino-naphthalin (78%) und aus 1-Azido-naphthalin und Benzol (l-Amino-4-phmyl-naphthalin (82%). 

Substituted amino groups in the 5-position interfere with the course of the reaction, possibly because of nitrosamine formation thus, 3-amino-5-methylamino- and 3-amino-5-anilino-l,2,4-thiadiazole afford the corresponding 3-chloro derivatives (311 R = MeNH PhNH X = Cl) in only minute yields (5 and 8%, respectively).178... 

The radioprotective action of 3,5-diamino-l,2,4-thiadiazole, its 3-toluene-p-sulfonyl derivative, and the corresponding 5-methyl-amino- and 5-anilino analogs has been determined.218 Administration of the parent compound results in 69% survival in mice after 900 r whole body X-radiation, a result that compares favorably with the effects of such established protectors as AET ([Pg.202]

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