Wieland, Theodor

Wieland, Theodor (1913-1995), Professor of Organic Chemistry (1951-1968) at Erank-furt/Main (Germany), and director of the department of natural product chemistry at the Max Planck Institute for medical research at Heidelberg (1968-1981). Besides other important contributions in natural science and peptide research, he made the mixed anhydride method available for modern peptide synthesis, and as early as 1953 described the basic principle of... 

Wieland Theodor bora in 1913 in Munich, he studied chemistry in Freiburg Brsg. and Munich where he received his Dr. phil. in 1937. From 1937 until 1946 he was assistant, (Lecturer 1941), with Richard Kuhn at the Kaiser-Wilhelm/Max-Planck-Institute in Heidelberg. In 1946 he became Prof, at the Univ. of Mainz. Between 1951 and 1968 he was Prof, and Director of the Institute of Organic Chemistry at the Univ. of Frankfurt. After R. Kuhn s death in 1967, he was appointed Director of the Department of Chemistry, later Natural Products, of the Heidelberg Institute until 1981. He is hon. prof, of the Universities of Frankfurt and Heidelberg. His contributions include electrophoresis on paper of amino acids, peptides and proteins, isoenzymes of lactate dehydrogenase (with G. Pfleiderer), mixed anhydride method of peptide synthesis (p. 79) peptides of Amanita mushroonis (p. 211). 

Wieland, Theodor. The world of peptides a brief history of peptide chemistry/T. Wieland, M. Bodanszky. p. cm. Includes bibliographical references. ISBN-13 978-3-642-75852-2... 

The importance of the thioesters was realized at the beginning of the 1950s by Theodor Wieland from the University of Frankfurt am Main (Wieland and Pflei-derer, 1957), who used aminoacyl mercaptans as activated amino acids in peptide syntheses (see Sect. 5.3). Thus, 30 years later, this area of basic research came to be useful for prebiotic chemistry. 

Looking back, I must thank my academic teachers, Gerhard Pfleiderer and Theodor Wieland, for introducing me to biochemistry and natural product chemistry, and thus to the phenomenon of life , the origins of which are still hidden in the darkness of the unknown. 

Curtius, Theodor (1857-1928). Ger scientist who published many papers on the prepn props of various org compds, many of which are explosive. Curtius was editor for many years of the Journal fur Praktische Chemie Refs 1)A.Darapsky, ZAngChem 40, 581-83 (1927) (Biographical note) 2)H.Wieland, Z AngChem 41, 193-94 (1928) (Obituary) 3)A. Darapsky, JPraktChem 125, 1-22(1930) (A review of Curtius work, with photograph)... 

Dr. Bernd Gallenkamp Dr. Wolfgang Hofer t Dr. Bernd-Wieland Kruger Dr. Fritz Maurer Dr. Theodor Pfister ... 

Dedicated to Professor Theodor Wieland on the occasion of his 65th birthday (June 1978)... 

Muscarine from the mushroom. Amanita muse aria, has become a valuable biochemical tool for measuring peripheral effects on cholinergic receptors (see Volume 23 of this series). Each year Phalloidin from the mushroom. Amanita phalloides, causes several deaths in Europe from mushroom poisoning and has been the subject of a book by Theodor Wieland. In this volume, the subjects of alkaloids and mushrooms are brought together in a paper written by a team of experts from Poland in Alkaloids from Mushrooms. ... 

Professor Dr. Theodor Wieland Max-Planck-Institut fiir Medizinische Forschung JahnstraBe 29, 6900 Heidelberg, FRG... 

I am very much indebted to all of my colleagues with whom I have had the opportunity to cooperate in studying the potential of the Merrifield synthesis. Above all I like to express my gratitude to my teacher. Professor Dr. Theodor Wieland, Heidelberg, for his boundless encouragement and support in my efforts in the field of peptide synthesis, particularly in its polymer phase bound version. Last but not at least I wish to thank Miss Hildegard Leyden. With infinite patience and great accuracy she typed the manuscript in addition to her daily duties. 

Von THEODOR WIELAND und GERHARD PFLEIDERER, Frankfurt Main, Deutschland... 

Theodor Wieland, Institut filr organische Chemie, Johann Wolfgang Goethe Universitdl, Frankfurt am Main, Germany... 

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