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Whole genome shotgun approach

The international public (HGP) and American private (Celera) efforts to determine the sequence of the human genome exploited different approaches [9,10,35], It is still not clear whether Celera s whole genome shotgun sequencing (WGC) approach was really efhcient as they used publicly available data and it is not known to what extent. [Pg.69]

Figure 1.2-7. Two main approaches used to sequence the human genome. The hierarchical approach is based on creation of clone contigs covering the whole genome and shotgun sequencing of individual cosmid/BAC/PAC clones (a). The whole genome shotgun sequencing scheme (WGS) shown in (b) is based on pair-end sequencing of small-insert and selected BAC/PAC clones. See text for details. Figure 1.2-7. Two main approaches used to sequence the human genome. The hierarchical approach is based on creation of clone contigs covering the whole genome and shotgun sequencing of individual cosmid/BAC/PAC clones (a). The whole genome shotgun sequencing scheme (WGS) shown in (b) is based on pair-end sequencing of small-insert and selected BAC/PAC clones. See text for details.
See other pages where Whole genome shotgun approach is mentioned: [Pg.634]    [Pg.184]    [Pg.634]    [Pg.184]    [Pg.13]    [Pg.183]    [Pg.66]    [Pg.1118]    [Pg.94]    [Pg.36]    [Pg.564]    [Pg.396]    [Pg.80]    [Pg.90]    [Pg.91]    [Pg.84]    [Pg.422]    [Pg.255]    [Pg.54]    [Pg.68]    [Pg.1104]    [Pg.83]   
See also in sourсe #XX -- [ Pg.634 ]

See also in sourсe #XX -- [ Pg.564 ]



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