Wheat bran diets colon tumor incidence

Colon Tumor Incidence in Female F344 Rats Fed Diets Containing Pectin, Alfalfa, or Wheat Bran and Treated with... 

The effect of dietary wheat bran and dehydrated citrus fiber at 15% level and 5% dietary fat on intestinal carcinogenesis induced by AOM and DMAS was studied in male F344 rats (44,45). Composition of diets was adjusted so that all animals in different experimental groups consumed approximately the same amount of protein, fat, minerals and vitamins. The animals fed the wheat bran or citrus fiber and treated with AOM had a lower Incidence (number of animals with tumors) and multiplicity (number of tumors/tumor bearing rat) of colon tumors and tumors of the small Intestine than did those fed the control diet and treated with AOM (Table II 15). Although 15% purified pectin in the diet (41) inhibited the colon tumor incidence better than did 15% dehydrated citrus fiber, in this study the Inhibition of colon tumor multiplicity was more pronounced with the dehydrated citrus fiber compared with purified pectin. Because dehydrated citrus fiber contains about 20% pectin, the pectin content of this diet was considerably lower than that of the diet used in... 

Colon Tumor Incidence in F344 Male Rats fed Diets Containing Wheat Bran or Citrus Fiber... 

The animals fed the wheat bran and Created with DMAS had a lower incidence and multiplicity of colon and small intestinal tumors compared Co those fed the control diet and treated with DMAB (Tables III and IV 44). Animals fed the diet containing citrus fiber developed fewer DMAfi-lnduced small Intestinal tumors than did the rats fed the control diet. 

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