What Holds Our World Together

Once the structure of an oligomer is determined, the question remains why the oligomer has precisely this and no other structure. How does this specificity come about Which areas of the subunits are responsible for the oligomer formation How are these contact sites arranged geometrically The following help provide answers. 

(1992). Specification of Subunit Assembly by the Hydrophilic Amino-terminal Domain of the Shaker Potassium Channel, Science 257 1225-1230. 

Maniolos, M. (1990). Transmembrane Helical Interactions and the Assembly of the T Cell Receptor Complex,  

Pakula, A., and Simon, M. (1992). Determination of Transmembrane Protein Structure by Disulfide Cross-linking The E. coli Tar Receptor, Proc. Natl. Acad. Sci. USA 89 4144—4148. 

Sumikawa, K. (1992). Sequences on the N-terminus of Ach Receptor Subunits Regulate Their Assembly, Mol. Brain Res. 13 349-353. 

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