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Warfarin teratogenic effects

Teratogenic effects have been observed in humans after maternal warfarin exposure. The effects are primarily seen in the nasal region of the fetus and include nasal hypoplasia, bone stippling, and mental retardation. Central nervous system abnormalities due to localized hemorrhaging and scarring have occurred after second- or third-trimester exposures, whereas exposure during early pregnancy may result in dysmorphism. ... [Pg.740]

SAFETY PROFILE Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. An experimental teratogen. Human reproducdve effects by ingestion developmental abnormalities of the cardiovascular system, stillbirth, and unspecified neonatal effects. An andcoagulant. See also WARFARIN and ESTERS. When heated to decomposidon it emits acrid and irritadng fumes. [Pg.194]


See other pages where Warfarin teratogenic effects is mentioned: [Pg.476]    [Pg.323]    [Pg.40]    [Pg.262]    [Pg.153]    [Pg.448]    [Pg.58]    [Pg.260]    [Pg.124]    [Pg.98]    [Pg.776]    [Pg.124]   
See also in sourсe #XX -- [ Pg.726 ]

See also in sourсe #XX -- [ Pg.959 , Pg.964 ]

See also in sourсe #XX -- [ Pg.59 ]




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