Vomiting, severe

Severe intractable vomiting Severe intractable diarrhea... 

Procarbazine -alkylating agent cell cycle independent -bone marrow suppression—prolonged -nausea and vomiting—severe tolerance often develops with repeated dosing -mucocutaneous effects (mucositis, stomatitis, diarrhea) -rash, hives, photosensitivity -interstitial pneumonitis -CNS toxicity—seizures, lethargy, headache, ataxia -flu-like syndrome -azoospermia and amenorrhea almost universal... 

A 15 -year-old male attempts suicide with a liquid that causes intense abdominal pain, skeletal muscle cramps, projectile vomiting, severe diarrhea, and difficulty swallowing. On examination, he is found to be volume depleted and is showing signs of alteration of consciousness. Which of the following may account for these symptoms ... 

CDC Case Definition An illness characterized by diarrhea and/or vomiting severity is variable. Laboratory criteria for diagnosis is (1) isolation of toxigenic (i.e., cholera toxin-producing) V. cholerae Ol or0139 from stool orvomitus or (2) serologic evidence of recent infection. 

For pentamidine, side effects include hypotension, tachycardia, nausea, vomiting, severe hypoglycemia or hyperglycemia, pancreatitis, irreversible diabetes mellitus, elevated transaminases, nephrotoxicity, leukopenia, and cardiac arrhythmias. 

AZP, the most-recently characterized marine seafood poisoning, is associated with eating shellfish contaminated with azaspiracids. The first human intoxications attributed to AZP occurred in the Netherlands, and the symptoms included those similar to DSP (i.e., nausea, vomiting, severe diarrhea, and stomach cramps). However, although chemical analyses did not identify significant levels of the diarrhetic shellfish poisons, they identified a new class of toxins (James et ah, 2003a). 

Fructose intolerance causes vomiting, severe hypoglycemia, and kidney and liver damage that may lead to organ failure and death. 

Severe iron poisoning is manifested as vomiting, severe abdominal pain, diarrhea, and dehydration, followed by hyperventilation, pallor or cyanosis, and cardiovascular collapse. 

Notify the physician if diarrhea, difficulty breathing, increased salivation, irregular heartbeat, muscle weakness, nausea and vomiting, severe abdominal pain, or increased sweating occurs... 

A hypersensitivity reaction may be life-threatening. Signs and symptoms include fever, rash, fatigue, intractable nausea and vomiting, severe diarrhea, abdominal pain, cough, pharyngitis, and dyspnea. 

Adverse effects include pancreatitis with symptoms of nausea, vomiting, severe abdominal or stomach pain and is more frequent in children. Paresthesia and peripheral neuropathy with tingling, burning, numbness or pain in the hands and feet are also more frequent in children. 

A 24-year-old woman briefly lost consciousness and had nausea and vomiting several minutes after smoking marijuana. She had hyporeflexia, atrial fibrillation (maximum 140/minute with a pulse deficit), and a blood pressure of 130/80 mmHg. Echocardiography was unremarkable. Within 12 hours, after metoprolol, propafenone, and intravenous hydration with electrolytes, sinus rhythm was restored. 

A missed oral dose allows even less latitude than the combined pill. If a dose is more than 3 hours late it should be taken at once and a barrier method used for 7 days. Act similarly where there has been vomiting, severe diarrhoea, or if an enzyme-inducing drug has been taken. 

The safety of carbon dioxide in vena cavography has been investigated in 119 patients (aged 17-89 years, 65 men). Patients with intracardiac shunts, severe pulmonary compromise, or non-dialysis-dependent renal insufficiency were excluded. Two patients developed mild adverse effects one had nausea that resolved spontaneously and the other vomited several minutes after the administration of carbon dioxide but needed no treatment. The diagnostic quality of the venography was comparable to that with iodinated contrast media. The authors concluded that carbon dioxide cavography is well tolerated and is especially valuable in patients with a history of a reaction to iodinated contrast material or renal insufficiency. 

In patients with ovarian cancer, the combination of inter-leukin-3 with high-dose carboplatin was poorly tolerated severe fever, malaise, protracted nausea, vomiting, severe hypotension, and nephrotoxicity required withdrawal of interleukin-3 in 60% of patients when interleukin-3 was given only 24 hours after high-dose carboplatin (18). 

Two of 37 patients experienced gastralgia and vomiting, severe enough to stop therapy (SEDA-7,191). In another series of 40 patients, five had gastralgia and nausea, requiring withdrawal of therapy in three. 

An 8-year-old girl with acute promyelocytic leukemia was given cytarabine, etoposide, idarubicin, and tretinoin 25 mg/m /day (43). Five days later she developed fever, pleural effusions, and ascites, but the symptoms resolved spontaneously. On day 65 (cumulative dose of tretinoin 1.6 g/m ) she had nausea and vomiting, severe headache, and diplopia. There was paralysis of the left trochlear nerve bilateral papilledema. A cranial MRI scan was normal. The intracranial pressure was not measured. Tretinoin was withdrawn and she was given glucocorticoids, mannitol, acetazolamide, and pethidine. Her symptoms resolved within 2 days. 

Adverse reactions Nausea, abdominal pain, Gl bleeding, ulcers, heartburn, rash, dizziness Nausea, vomiting, severe diarrhea, abdominal pain Short-term use insomnia, nervousness, Gl upset, increased appetite Headache, nausea, vomiting, anorexia Most common is skin rash... 

The first human acute intoxications attributed to newly described azaspiracid poisoning (AZP) occurred in the Netherlands after consumption of contaminated shellfish. The symptoms were similar to the nausea, vomiting, severe diarrhea, and stomach cramps of DSP. AZP in humans has been reported throughout Europe since 1995, and azaspiracids have been found in shellfish harvested in Spain, France, and northern Europe. 

Chronic use of high doses of the long-acting barbiturates may produce psychological and physical dependence. Abrupt discontinuation of therapy may result in withdrawal signs and symptoms. Mild withdrawal may include weakness, anxiety, muscle twitching, insomnia, nausea, and vomiting. Severe withdrawal may consist of hallucinations, autonomic instability, delirium, and seizures. Unlike opioid withdrawal. 

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