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Voltage-dependent Na+ Channels

Inwardly Rectifying K+ Channels Voltage-dependent Na+ Channels... [Pg.13]

Voltage-dependent Na+ Channels Voltage-dependent Ca2+ Channels (3-Adrenergic System Cardiac Glycosides... [Pg.101]

Voltage-dependent Na+ Channels Nicotinic Receptors Ionotropic Glutamate Receptors Voltage-gated K+ Channels Inward Rectifier K+ Channels... [Pg.487]

Analgesics Local Anaesthetics Voltage-dependent Na+Channels Pain and Nociception... [Pg.829]

All these postsynaptic events last only for a few milliseconds synaptic transmission through LGICs is fast. When the postsynaptic cell membrane is sufficiently depolarized, voltage-dependent Na+ channels open and an action potential is generated. [Pg.1172]

Voltage-dependent Na Channels. Table 1 Mammalian sodium channel a subunits... [Pg.1306]

The voltage sensor is the part of a channel protein responsible for detection of the membrane potential. A voltage sensor of the voltage-dependent Na+ channel was predicted by Hodgkin and Huxley in 1952. Positively charged amino acid residues in S4 of each repeat play an essential role as the voltage sensor. [Pg.1313]

This chapter summarizes recent work on the molecular basis of the toxic actions of ciguatoxin and brevetoxins. It is shown (i) that the molecular target for these toxins is the voltage-dependent Na channel of excitable tissues arid (ii) that ciguatoxin and brevetoxins share a common receptor site on the Na channel. [Pg.193]

All these results are clear indications that CTx and PbTx have similar modes of action and that they increase the membrane permability of excitable cells to Na ions by opening voltage-dependent Na channels. This action fully accounts for the toxicity of ciguatoxin and brevetoxins. [Pg.195]

Several mechanisms have been suggested for the action of valproic acid, including blockade of voltage-dependent Na+ channel, potentiation of y-aminobutryric acid... [Pg.231]

Gleitz J, Beile A, Peters T. (1995). (+/-)-Kavain inhibits veratridine-activated voltage-dependent Na(+)-channels in synaptosomes prepared from rat cerebral cortex. Neuropharmacology. 34(9) 1133-38. [Pg.496]

See other pages where Voltage-dependent Na+ Channels is mentioned: [Pg.127]    [Pg.128]    [Pg.245]    [Pg.525]    [Pg.703]    [Pg.704]    [Pg.800]    [Pg.808]    [Pg.1110]    [Pg.1171]    [Pg.1197]    [Pg.1305]    [Pg.1305]    [Pg.1306]    [Pg.1307]    [Pg.1312]    [Pg.1313]    [Pg.1505]    [Pg.192]    [Pg.193]    [Pg.193]    [Pg.193]    [Pg.195]    [Pg.196]    [Pg.322]    [Pg.716]    [Pg.720]    [Pg.15]    [Pg.16]    [Pg.222]   


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Channel voltage

Na+ channel

Voltage dependence

Voltage dependent

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