Virus particles genetic engineering

Figure 6.1 An RNA viral gene therapy vector, engineered to carry the genetic information for a protein product, is incubated with blood or bone marrow cells removed from a patient. The foreign DNA sequence integrates into the cell s genetic material and when the cells are returned to the patient, they direct the production of the protein product. RNA gene therapy vectors are engineered to be unable to direct the production of new virus particles.

Fig. 15.6 Schematic representation of three important interfaces available for genetic and chemical engineering of virus-like particles (VLPs) and vims nanoparticles (VNPs).

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