Vibrational spectroscopic imaging

The Scanning Tunneling Microscope has demonstrated unique capabilities for the examination of electrode topography, the vibrational spectroscopic imaging of surface adsorbed species, and the high resolution electrochemical modification of conductive surfaces. Here we discuss recent progress in electrochemical STM. Included are a comparison of STM with other ex situ and in situ surface analytic techniques, a discussion of relevant STM design considerations, and a semi-quantitative examination of faradaic current contributions for STM at solution-covered surfaces. Applications of STM to the ex situ and in situ study of electrode surfaces are presented. 

Preparation of Soft Tissue for Vibrational Spectroscopic Imaging... 

The possibility of inducing brain tumors in a small animal model opens the route to excihng studies for the applicahon and optimization of acquisition techniques and data analysis algorithms for vibrational spectroscopic images. 

Although in its early stages, one can be optimistic that vibrational spectroscopic imaging has the potential to become fully accepted as a diagnostic tool for soft tissues, with sufficient sensitivity and specificity for rapid and nondestructive in vitro, ex vivo and in vivo analyses. 

The development, aging, pathology, microstructure and compositional basis of the mechanical functioning of musculoskeletal tissue have been major application areas for vibrational spectroscopic imaging [16, 22]. For these applications, the... 

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