Vibrational hard tissue

Connective tissues have often been reported in Raman and FT-IR images adjacent to epitheUum or carcinomas. Articular cartilage [15], ECM damage [16], and sarcoma, which is a neoplastic process originating within connective tissue [17], were studied by Raman spectroscopy. Applications of vibrational spectroscopic imaging to bone, which belongs to supportive connective tissue and is considered as hard tissue, are described in Chapter 4 of this book. 

Elements of Hard Tissues, Detectable by Vibrational Spectroscopy... 

Vibrational spectroscopy provides information on the functional groups present in the mineral and organic matrix components of hard tissues, as well as their molecular neighborhood [2,3]. The mineralized tissue components and properties that can be easily determined through both Fourier transform infrared (FT-IR) or Raman spectroscopic analysis and their biological significance are as follows ... 

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