Vero-E6 cells

Researchers at SRMLSC recently developed a HTS that allowed the identification of potential inhibitors of the severe acute respiratory syndrome coronavirus (SARS CoV) from large compound libraries [34], The luminescent-based assay, which measured the inhibition of SARS CoV-induced cytopathic effects (CPE) in Vero E6 cells, was validated with two different diversity sets of compounds against the SARS CoV. The hit rate for both libraries was approximately 0.01%. 

Table 1 In vitro antiplasmodial activity (IC50 S.D.) of the extracts of selected medicinal plants against P. falciparum W2 and D6 clones, and cytotoxicity on mammalian Vero E6 cells, with Selectivity Index...

Plant species P. falciparum (W2) (pg/ml) P. falciparum (D6) (pg/ml) Vero E6 cells CC50 (lig/ml) Selectivity Index CCso/D6... 

The cytotoxic concentration causing 50% cell lysis and death (CC50) was determined for the extracts where kidney cells of African green monkey (Vero E6) were seeded at a concentration of 2.5x10 cells/well in 24-well plates and grown in minimum essential... 

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