Ventilator-induced lung injury

Dolinay, T., Szilasi, M., Liu, M., Choi, A.M. (2004). Inhaled carbon monoxide confers anti-inflammatory effects against ventilator-induced lung injury. Am. J. Respir. Crit. Care Med. 170 613-20. 

Lung diseases characterized by remodeling of the lung parenchyma or airway wall involve alterations in PGs. Changes in PGs have been best characterized in pulmonary fibrosis and, to a lesser extent, in asthma. Their roles in such diseases as emphysema, lung cancer, and ventilation-induced lung injury have not been as well defined. 

Dos Santos CC, Slutsky AS. Invited review mechanisms of ventilator-induced lung injury a perspective. J Appl Physiol 2000 89 1645-1655. 

F6. Foda, H. D., Rollo, E. E., Drews, M., Conner, C., Appelt, K., ShaUnsky, D. R., Zucker, S., Foda, J. D., Rollo, E. E., Drews, M., et al.. Ventilator-induced lung injury upregulates and activates gelatinases and EMMPRIN Attenuation by the synthetic matrix metalloproteinase inhibitor, Prinomastat. Am. J. Respir. Cell Mol. Biol. 25, 717-724 (2001). 

Belperio JA, Keane MP, Lynch JP 3rd, Stricter RM. The role of cytokines during the pathogenesis of ventilator-associated and ventilator-induced lung injury. Semin Respir Crit Care Med 2006 27(4) 350-364. 

Practical Pulmonary and Critical Care Medicine Disease Management, edited by Zab Mosenifar and Guy W. Soo Hoc Ventilator-Induced Lung Injury, edited by Didier Dreyfuss, Georges... 

A. Lung Stretch and Ventilator-Induced Lung Injury... 

Dreyfuss D, Savmon G. Ventilator induced lung injury lessons from experimental studies. Am J Respir Crit Care Med 1998 157 294-323. 

Rich BR, Reickert CA, Sawada S, et al. Effect of rate and inspiratory flow on ventilator induced lung injury. J Trauma 2000 49 903-911. 

Tremblay LN, Slutsky AS. Ventilator-induced lung injury from the bench to the bedside. 

Mechanical ventilation is associated with several complications including respiratory muscle weakness, ventilator-induced lung injury, trauma to the upper airway, and ventilator-associated pneumonia (14,15). Therefore, minimizing the duration of invasive ventilatory... 

Uhllg, S. 2002. Ventilation-induced lung injury and mechanotransduction Stretching it too far American Journal of Physiology-Lung Cellular and Molecular Physiology 282(5) L892-6. 

Syrkina, O., B. Jafari et al. 2008. Oxidant stress mediates inflammation and apoptosis in ventilator-induced lung injury. Respirology 13 333-340. 

Plotz, F.B., Slutsky, A.S., VanVught, A.J., and Heijnen, C.J. 2004. Ventilator-induced lung injury and multiple system organ failure A critical review of facts and hypotheses. Intensive Care Med 30 1865-72. 

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