VE-cadherin

Bobryshev YV, Cherian SM, Inder SJ, Lord RSA (1999) Neovascular expression of VE-cadherin in human atherosclerotic arteries in its relation to intimal inflammation. Cardiovasc Res 43 1003-1017... 

Carmeliet P, Lampugnani MG, Moons L, et al. Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis. Cell 1999 98(2) 147-157. 

Papadias C, Economou E, Creatsas G. Effect of hormone therapy and raloxifene on serum VE-cadherin in postmenopausal women. Fertil Steril 2004 82 634-8. 

Fig. 3. A comparison of cell-cell and cell-substrated anchoring junctions. (A) Desmosomes anchor keratin filaments through desmoplakin. One half of a desmosome, which is an intercellular junction that anchors intermediate filaments (IFs) to the plasma membrane, is shown. The transmembrane desmosomal cadherins, desmogleins (Dsg) and desmocollins (Dsc), mediate adhesion through their extracellular domains, and associate with plakophilins (Pkp) and plakoglobin (Pg) through their cytoplasmic domains. These proteins in turn interact with the N-terminus of the plakin family member desmoplakin, which anchors IF to the junction through its G-terminus. (B) Endothelial VE-cadherin-based junctions anchor vimentin through...

VE-cadherin adhesion molecule related to endothelial cells... 

VE)-cadherin and platelet endothelial cell adhesion molecule-1 (PECAM-1). VE-cadherin is an endothelial-specific Ca " -regulated protein that is linked to the cytoskeleton via catenins (Fig. 1). PECAM-1, also known as CD31, is a key participant in the migration of blood-borne cells across the BBB. Changes in the adherent junction proteins can lead to increased paracellular permeability (Abbruscato and Davis, 1999) and leukocyte trafficking in the CNS (Newman, 1994 Garrido-Urbani et al., 2008). 

Elmquist, A., Lindgren, M., Bartfai, T., and Langel, U. (2001) VE-cadherin-derived cell-penetrating peptide, pVEC, with carrier functions. Exp. Cell. Res. 269, 237-244. 

Gotsch U, Borges E, Bosse R, Boggemeyer E, Simon M, Mossmann H, Vestweber D VE-cadherin antibody accelerates neutrophil recruitment in vivo. J Cell Sci 1997 110 583-588. 

Lampugnani MG, Corada M, Caveda L, Breviario F, Ayalon O, Geiger B, Dejana E The molecular organization of endothelial cell to cell junctions Differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin). J Cell Biol 1995 129 203-217. 

Gavard, J. Endothelial permeability and VE-cadherin a wacky comradeship. Cell. Adh. Migr. 8(2), 158-164 (2014)... 

Conway, D.E., et al. Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1. Curr. Biol. 23(11), 1024—1030 (2013)... 

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