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Vascular endothelial growth factors clinical trials

Clinical trials of vascular endothelial growth factor... [Pg.359]

A variety of growth factors and chemokines convincingly increase the formation of small blood vessels in experimental models, Most clinical trials to date involve the transfer of vascular endothelial growth factor (VEGF) or fibroblast growth factor (FGF) using several delivery strategies. [Pg.393]

Goss G et al (2009) A phase I and pharmacokinetic study of daily oral cediranib, an inhibitor of vascular endothelial growth factor tyrosine kinases, in combination with cisplatin and gemcitabine in patients with advanced non-small cell lung cancer a study of the national cancer institute of Canada clinical trials group. Eur J Cancer 45 782-788... [Pg.242]

Weng D E, Masci P A, et al. (2005). A phase I clinical trial of a ribozyme-based angiogenesis inhibitor targeting vascular endothelial growth factor receptor-1 for patients with refractory solid tumors. Mol. Cancer Ther. 4 948-955. [Pg.1078]

Schneider BP et al. Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymoiphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer ECOG 2100. Journal of Clinical Oncology 2008 26 4672-4678. [Pg.362]

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