Variant surface glycoprotein

Bangs, J.D., Andrews, N.W., Hart, G.W., and Englund, P.T. (1986) Post-translational modification and intracellular transport of a trypanosome variant surface glycoprotein./. Cell Biol. 103, 255-263. 

Commonly attached at 03 of Man-I of the Tryp. brucei variant surface glycoprotein GPI anchor is a digalactose branch, which may further carry additional D-galactose (Gal) units [13], In 1991, the first total synthesis of the common region of the GPI anchor of Tryp. brucei was accomplished by the Ogawa group [14, 32], The Gal... 

Ferguson, M.A., Low, M.G., and Cross, G.A., 1985, Glycosyl-sn-l,2-dimyristylphosphatidylinositol is covalently linked to Trypanosoma brucei variant surface glycoprotein. J. Biol. Chem. 260 ... 

The first complete structural characterization of a GPI, achieved by Ferguson and coworkers in 1988, was of the T. brucei variant surface glycoprotein (VSG) anchor [9]. This study was assisted by the fact that the African trypanosome system exhibits abundant VSG (ca. 10 copies per cell) [10], which also facilitated the development of the first cell-free... 

T. cruzi small mucin-like gene family TcTS, Trypanosoma cruzi trans-sialidase THF, tetrahydrofuran TMSOTf, trimethylsilyl trifluoromethanesulfonate TRR, Thr-rich region TSSA, trypomastigote small surface antigen UDP, uridine diphosphate VSG, variant surface glycoprotein. 

M. A. J. Ferguson, S. W. Homans, R. A. Dwek, and T. W. Rademacher, Glycosyl-phosphatidylinositol moiety that anchors Trypanosoma brucei variant surface glycoprotein to die membrane, Science, 239 (1988) 753-759. 

W. J. Masterson, T. L. Doering, G. W. Hart, and P. T. Englund, A novel pathway for glycan assembly biosynthesis of the glycosyl-phosphatidylinositol anchor of the trypanosome variant surface glycoprotein, Cell., 56 (1989) 793-800. 

GTPyS guanosine 5 -0-(3-thiotriphosphate) VSG variant surface glycoprotein... 

Doering, T. L., Pessin, M. S., Hoff, E. F., Hart, G. W., Raben, D. M. and Englund, P. T. (1993) Trypanosome metabolism of myristate, the fatty acid required for the variant surface glycoprotein membrane anchor. J. Biol. Chem. 268 9215-9222. 

Bulow, R. and Overath, P. (1986) Purification and characterization of the membrane-form variant surface glycoprotein hydrolase of Trypanosoma brucei. J. Biol. Chem. 261 11918-11923. 

Paindavoine, P., Rolin, S. van Assel, Geuskens, M. et al. (1992) A gene from the variant surface glycoprotein expression site encodes one of several transmembrane adenylate cyclases located on the flagellum of Trypanosoma brucei. Mol. Cell. Biol. 12 1218-1225. 

Schell, D., Evers, D., Preis, D. et al. (1991) A transferrin binding protein of Trypanosoma brucei is encoded by one of the genes of the variant surface glycoprotein expression site. EMBO J. 10 1061-1066. 

Seyfang, A., Mecke, D. and Duszenko, M. (1990) Degradation, recycling, and shedding of Trypanosoma brucei variant surface glycoprotein. J. Protozool. 37 546-552. 

Sheader K, et al. (2005). Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes. Proc. Natl. Acad. Sci. USA. 102(24) 8716-8721. 

Ferguson MAJ, Homans SW, Dwek RA, Rademacher TW. Glycosyl-phos-phatidylinositol moiety that anchors Trypanosoma brucei variant surface glycoprotein to the membrane. Science 1988 239 753-759. 

Trypanosoma Variant surface glycoprotein Coat glycoprotein of 16-18... 

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