Vapor phase test

No histological changes occurred in the liver of adolescent male rats that were whole-body exposed to 0 or 900 ng/m Aroclor 1242 vapor 23 hours/day for 30 days (Casey et al. 1999). The generation of the vapor-phase test atmosphere was based entirely on the evaporation of a liquid PCB mixture using a system that did not create aerosol droplets, and the concentration and congener composition of the test atmosphere was well characterized. Limitations of this study include only one exposure level and liver end point and a relatively small number of animals (8/group) however, uptake of PCBs in the liver was confirmed by tissue analysis, and the exposure was sufficient to induce effects in other tissues, including the thyroid, which is known to be particularly sensitive to PCBs. 

Inhibitory Data of Anise Oil Obtained in the Vapor Phase Test... 

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