Vagina anomaly

An anorectal anomaly is usually identified clinically. There may be an anal dimple present on the perineum or there may be an apparently patent external orifice but with a digitally palpable membrane on examination. Meconium may be passed per urethra in boys or per vagina in girls. 

Mayer-Rokitansky-Kuster syndrome is the most common form of Class I anomaly and includes agenesis of uterus and vagina. 

DES-exposed uterus. DES (synthetic estrogen, di-ethyl-stilbestrol, 1948-1971) may induce abnormal myometrial hypertrophy in the fetal uterus forming small T-shaped endometrial cavities [33], as well as increase the risk of developing a dear cell carcinoma of the vagina [34]. The characteristic uterine abnormalities must be categorized in the group of complex uterine anomalies and may occur with or without the exposure of DES. 

Hricak H, Chang YC, Thurnher S (1988) Vagina evaluation with MR imaging. Part 1. Normal anatomy and congenital anomalies. Radiology 169 169-174... 

Failure of normal development of the mullerian ducts causes uterine agenesis or hypoplasia. Patients present with primary amenorrhea in adolescence. Agenesis or hypoplasia of any part of the genital tract (vagina, cervix, uterus, tubes) may occur either in isolation or, more, commonly, in combination. This relatively uncommon class of anomalies accounts for approximately 5% of mullerian duct anomalies. Vaginal agenesis is the most common subtype, and is often accompanied by uterine agenesis. 

Mayer-Rokitansky-Kuster-Hauser syndrome is a combined anomaly that belongs to this entity The typical form of this syndrome is characterized by congenital absence of the uterus and upper vagina. The ovaries and fallopian tubes are usually normal. The atypical form of the syndrome includes associated abnormalities of the ovaries and fallopian tubes and renal anomalies [32] (Fig. 16.16). 

It affects 1 in 4,000-5,000 otherwise normal (46 XX) girls. Mayer-Rokitansky-Kiister-Hauser syndrome type A (typical form) shows normal-appearing external genitalia, absence of the vagina and uterus, normal fallopian tubes, normal ovaries, and no renal anomalies. In type B (atypical form), the uterus may be normal except for the lack of a conduit to the introitus or may be rudimentary, commonly show-... 

Incomplete fusion of the distal segments of the two mullerian ducts results in various degrees of bifidity of the uterus and/or vagina (Jarcho 1946) (Fig. 7.6). Disorders of the lateral fusion are rare in the general population and, in the absence of obstruction, are asymptomatic during childhood or at puberty. However, these anomalies are more frequently encoun-... 

The incidence of prune belly syndrome is 1 out of 40,000 live births with a male predominance of 97%. By definition affected females cannot have the complete triad, and the urologic manifestations may often be less severe. In females, anomalies of the urethra, uterus, and vagina are usually present (Reinberg et al. 1991). Most cases occur sporadically, although familial occurrence has been described (Ramasamy et al. 2005). In selected cases, an association with trisomies 13,18, and 21 has been reported. 

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