User safety assessment process exposure

Cenfral to regisfration is fhe Chemical Safety Assessment (CSA), in which the registrant identifies and describes the conditions under which the manufacturing and use of a subsfance are considered to be safe. A CSA must be performed by registianfs for substances manufactured and imported in quantities at or above 10 tonnes per year and by downstream users if their uses are not addressed by their supplier. The CSA entails three major steps, hazard assessment, exposure assessment, and risk characterization, which are documented in the Chemical Safety Report (CSR). Figure 3.4 summarizes the process [95]. 

---