Use in postpartum hemorrhag

Clinical use is generally for the termination of pregnancy, but it is also used in postpartum hemorrhage. Following administration to the bladder, it has also proved useful in cyclophosphamide-induced hemorrhagic cystitis in bone marrow patients (342). 

Oxytocin is used to induce labor for conditions requiring early vaginal delivery such as Rh problems, maternal diabetes, preeclampsia, or ruptured membranes. It is also used to augment abnormal labor that is protracted or displays an arrest disorder. Oxytocin has several uses in the immediate postpartum period, including the control of uterine hemorrhage after vaginal or cesarean delivery. It is sometimes used during second-trimester abortions. 

Carboprost is a 15-methylated analogue of PGF2a- It is used in termination of pregnancy, in the management of labor, and to treat postpartum hemorrhage and uterine atony. 

Oxytocin is a hypothalamic nonapeptide that selectively stimulates the smooth muscle of the uterus and mammary glands. It is used in the induction or augmentation of labor and to prevent postpartum hemorrhage, and is well tolerated and effective in a wide range of infusion rates and concentrations. Contraindications to its use... 

Clinical use Induction of labor, to curtail bleeding postpartum, primarily responsible for dramatic decrease in maternal death secondary to postpartum hemorrhage. 

PH, the patient in the case above, has a postpartum hemorrhage after her delivery. Which of the following regimens can be used to stop the excessive bleeding ... 

Misoprostol may also prove useful in the treatment of postpartum hemorrhage and has also been used in organ transplantation. For example, it has been reported to improve kidney function in cyclosporin-treated patients who have received renal transplants (334). 

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