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Urinary tract antiseptics

Questionable carcinogen with experimental carcinogenic and tumorigenic data. Human mutation data reported. Used as an antibacterial agent and urinary tract antiseptic. When heated to decomposition it emits toxic fumes of NOx. [Pg.618]

The prodrug methenamine, described above in this chapter (Scheme S-17), can be considered a site-specific chemical delivery system for the urinary tract antiseptic agent fotmal-dehyde. The low pH of the urine promotes the hydrolysis... [Pg.156]

The urinary tract antiseptics inhibit the growth of many species of bacteria. They cannot be used to treat systemic infections because effective concentrations are not achieved in plasma with safe doses. However, because they are concentrated in the renal tubules, they can be administered orally to treat infections of the urinary tract. Furthermore, effective antibacterial concentrations reach the renal pelvis and the bladder. Treatment with such drugs can be thought of as local therapy—only in the kidney and bladder. [Pg.424]

Methenamine is a urinary tract antiseptic and prodmg that owes its activity to its capacity to generate formaldehyde. Methenamine is hexamethylenetetramine (hexamethylenamine). [Pg.424]

The urinary tract antiseptics inhibit the growth of many species of bacteria and can be used therapeutically because they are concentrated in the renal tubules. Effective antibacterial concentrations also reach the renal pelves and bladder. [Pg.727]

Urinary tract antiseptics Quinolones Nalidixic acid Cinoxacin... [Pg.442]

A family of antibiotics called sulfonamides, that stops the growth of bacteria, is used to treat UTI. These include trimethoprim-sulfamethoxazole (TMP-SMX) and cephalasporins. Aztreonam and fluoroquinolones are used as urinary tract antiseptics. Phenazopyridine (Pyridium) is used to treat pain from a UTI. [Pg.265]

Arbutin occurs in leaves of the pear tree Pyrus communis) and Arctostaphylos uva-ursi, and is a urinary tract antiseptic and diuretic. Arbutin is hydrolysed to hydroquinone in alkaline urine, this effect being strictly localised in the urinary tract. It is indicated for urinary tract infections, in particular cystitis, urethritis and prostatitis. [Pg.18]

See other pages where Urinary tract antiseptics is mentioned: [Pg.274]    [Pg.334]    [Pg.334]    [Pg.334]    [Pg.335]    [Pg.337]    [Pg.338]    [Pg.338]    [Pg.338]    [Pg.339]    [Pg.340]    [Pg.341]    [Pg.467]    [Pg.276]    [Pg.170]    [Pg.756]    [Pg.917]    [Pg.981]    [Pg.982]    [Pg.1071]    [Pg.146]    [Pg.357]    [Pg.112]    [Pg.112]    [Pg.2765]    [Pg.357]   
See also in sourсe #XX -- [ Pg.323 , Pg.324 , Pg.325 , Pg.326 , Pg.327 , Pg.327 , Pg.328 , Pg.328 , Pg.329 ]



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