Umbilicaria esculenta

Activity Against Human Immunodeficiency Virus (HIV). A sulfate (GE-3-S) prepared by chlorosulfonic acid treatment GE-3, a partially acetylated P(1 - 6)glucan from the lichen Umbilicaria esculenta (Miyoshi) Mink., inhibited the cytopathic effect of HIV in vitro (Hirabayashi et al. 1989). 

Umbilicaria esculenta (Miyoshi) Minks [syn. Gyrophora esculenta]... 

Umbilicaria esculenta Orcinol Aromatic APP Anti-inflammatory activity Kim et al. (1996)... 

A sulfate prepared by chlorosulfonation of GE-3-, a partially acetylated P—(I 6) glucan of the lichen Umbilicaria esculenta, inhibited the cytopathic effect of human inununodeficiency virus (HIV) and suppressed the HlV-antigen expression in Molt-4 (clone 8) cells (371). Emodin, 7-chloroemodin, 7-chloro-l-O-methylemodin and 5,7-dichloroemodin have exhibited antiviral activity 738, 72). Stiibler et al. 675,676) investigated the antiviral activity of the glucan lichenan. Seventeen depsides and depsidones have been examined for their inhibitory activity against HIV integrase 559). Yamamoto et al. 743) tested the extracts of numerous lichens on their inhibition of Epstein-Barr virus activation. 

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