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Types of HTS Assays

Protein-protein interaction Ligand-receptor binding (in vitro) [Pg.248]

Ligand-receptor binding (cell-based or mem brane-basedj e.g., ligand induced GTPyS binding [Pg.248]

Reporter gene assay (RGA), e.gv lucHerase, SEAP Secondary m essengers, e.g., Ca24(FLIPR), cAMP, IP3 J Cell-based ELISA e.g.,QytoBlDt Cell based physiological assay [Pg.248]

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