Tularemia dissemination

Those disseminating less easily, such as smallpox, tularemia, nerve agents, i.e. 

These are anthrax, smallpox, plague, botulism, tularemia, viral hemorrhagic fevers and ricin. They can disseminate and present a high risk on public health. Most of them require Level 4 Biosafety laboratories. 

E. Tularemia. Franciseila tularensis bacteria usually cause infection by exposure to bodily fluids of Infected animals or from the bites of ticks or mosquitoes. Aerosolized bacteria can also be Inhaled. An initial focal, suppurative necrosis is followed by bacterial multiplication within macrophages and dissemination to lymph nodes, lungs, spleen, liver, and kidneys. In the lungs, the lesions progress to pneumonic consolidation and granuloma formation and can result in chronic interstitial fibrosis. 

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