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Celastrol from Tripterygium wilfordii

Celastrol, from Tripterygium wilfordii (Celastraceae), inhibited mouse IL-1 production in peritoneal macrophages, induced by lipopolysaccharide, and IL-2 production in splenic lymphocytes induced by concanavalin A [107]. This plant also furnished three novel triterpenes named regeol A, B and C, belonging to the D A-friedooleanane type and nine known triterpenes [42]. In rheumatoid arthritis, the degree of inflammation of the articular synovial membrane has to do with the production of IL-1. For this reason, the... [Pg.132]


See other pages where Celastrol from Tripterygium wilfordii is mentioned: [Pg.280]    [Pg.718]    [Pg.661]    [Pg.147]   
See also in sourсe #XX -- [ Pg.30 , Pg.664 ]

See also in sourсe #XX -- [ Pg.664 ]




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Celastrol

Tripterygium wilfordii

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