Tripropyltin chloride

It seems that this anionic exchange would be relevant also to explain interactions of trialkyl tin (TAT) compounds (TET, tripropyltin chloride, TBT chloride) with the mitochondria. The current view of this phenomenon is that these compounds, by exploiting the Cl and OH gradient in energized mitochondria, behave as electroneutral OH /Cl exchangers. The crucial point of this new mechanism is that TATs enter the mitochondria as lipophilic cations [RsSn (rV)] and not as electroneutral compounds. The influx is followed by extrusion of the TAT compounds as electroneutral hydroxy compounds RsSnOH. ... 

Helium MIP-MS is also a very sensitive detection system for organotin compounds, such as tetraethyltin (TET), tetrabutyltin (TBT), triethyltin bromide (TET-Br), tripropyltin chloride (TPT-C1), tributyltin chloride (TBT-C1), and others, separated by CGC [213]. Detection limits at sub-pg levels were achieved, and linear dynamic ranges of at least three orders of magnitude were obtained. 

Photoexcited ketones react in the same way as alkoxyl radicals, and if, for example, a solution containing acetophenone and tripropyltin chloride is irradiated with UV light, the superimposed spectra of the propyl radical and the stannyloxyalkyl radical can be observed.89... 

The extraction of organotin compounds in aqueous samples is different from the other EDCs. Organotin compounds in aqueous samples can be extracted and derivatized at the same time. ° The organic solvent used in the extraction can be dichloromethane, hexane, or isooctane. A general procedure of extraction and derivatization is as follows 11 water is first buffered to pH 4.8 with 10 ml acetate buffer and spiked with internal standard tripropyltin chloride (TPrT) (about 100 ng). Samples are simultaneously extracted with 25 ml dichloromethane (or 25 ml hexane or isooctane) and derivatized with 1 to 3 ml of... 

Figure 12.7 Chromatogram of a mixture of (A) monomethyltin trichloride, (B) dimethyltin dichloride, (C) trimethyltin chloride, (D) triethyltin bromide and (E) tripropyltin chloride. The concentration of SDS was programmed from 0.02 M to 0.1 M for 2 min and constant at 0.1 M. Reprinted from Ref. 14 with permission of Applied Sj ctroscopy.

The calibration technique of standard addition is often used to minimize matrix effects in the quantification of organotins. External calibration is also used by many groups, howeveg the use of an internal standard is highly recommended with the nature of the best compound to use dependent on the measurement system involved. Tripropyltin chloride has been used by many groups as a surrogate to monitor the whole method process, and species such as tetra-butyltin and tetrapentyltin have been used as internal standards added just prior to GC analysis. 

Nonorganic solvent systems in which the Lewis base is dissolved in water and a liquid Lewis acid, such as tripropyltin chloride, is used neat. 

Figure 3.4 shows a typical MLC-ICP-MS chromatogram. A 0.1 M SDS micellar mobile phase was used with a C g column for the separation of trimethyltin chloride (TMT-Cl), triethyltin bromide (TET-Br), and tripropyltin chloride (TPrT-Cl). Additionally, monomethyltin trichloride (MMT-Cl), dimethyltin dichloride (DMT-Cl), and trimethyltin chloride (TMT-Cl) were separated using a 0.02 M SDS mobile phase. The flow rate was 1 ml min for both separations. 

MMT-Cl = monomethyltin trichloride DMT-DCl = dimethyltin dichloride TMT-C1 = trimethyltin chloride TET-Br = triethyltin bromide TPrT-Cl = tripropyltin chloride. 

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