Triple Antibiotic

See Table 47-4 for systemic treatment of an infected pressure sore. A short, 2-week trial of topical antibiotic (silver sulfadiazine or triple antibiotic) is recommended for a clean ulcer that is not healing or is producing a moderate amount of exudate despite appropriate care. 

C) Triple antibiotics (bacitracin, Polymyxin B, and neomycin) ointment... 

OTC Topical with bacitracin (Bacimyxin, Polysporin) with bacitracin, neomycin (Neosporin, Triple Antibiotic) with bacitracin, neomycin, lidocaine (Lanabiotic, Spectrocin) with gramicidin (Polysporin) with gramicidin, lidocaine (Lidosporin, Polysporin Burn Formula) with gramicidin, neomycin (Neosporin)... 

Neomycin 0.35% Triple Antibiotic Ophthalmic Ointment (Various)... 

Berger RS, Pappert AS, Van Zile PS, Cetnarowski WE. A newly formulated topical triple-antibiotic ointment minimizes scarring. Cutis 2000 65(6) 401. ... 

Staphylococci are the most eommon cause of endocarditis in IV drug abusers. A triple-antibiotic regimen of ampicillin, nafcillin, and gentamicin is appropriate if there is no hypersensitiv-... 

Staphaseptic is a new approach to wound care. Use in place of a triple antibiotic or poly-biotic ointment as an everyday infection prevention product for minor cuts, scrapes, abrasions and bums. Simply cleanse the wound and apply Staphaseptic before a bandage. For a free sample contact JaneUe Nichols at jnichols teclabsinc. com. Tec Labs, www.teclabsinc.com, (800) 482-4464. Circle 279... 

Beginning in the 1980s research directed toward the isolation of new drugs derived from natural sources identified a family of tumor inhibitory antibiotic substances characterized by novel struc tures containing a C C—C=C—C C unit as part of a nine or ten membered ring With one double bond and two triple bonds (-ene + di- + -yne) these com pounds soon became known as enediyne antibiotics The simplest member of the class is dynemian A most of the other enediynes have even more compli cated structures... 

Edmondson, K.H. Disposal of antibiotic spent beers by triple effect evaporation. Proceedings of the 8th Industrial Waste Conference, Purdue University, West Lafayette, IN, 1953 46-58. 

Quadruple therapy regimens (2 antibiotics, bismuth, antisecretory agent) Like triple therapy regimens, these have proven to be effective in H. pylori eradication. The primary disadvantage of these regimens is compliance. In addition, because of the variety and number of medications used, adverse effects are more common in... 

A. One-week triple therapy regimes combining a proton pump inhibitor with two antibiotics chosen from amoxicillin, clarithromycin and metronidazole are effective in about 90% of cases. 

Use of these as part of triple therapy for eradication of Campylobacter pylori has been almost completely supplanted by antacid and antibiotic treatment. 

Finally, it is universally accepted at present that Helicobacter pylori infection has a definitive ethiological role in peptic ulcer disease, and that erradication therapy is warranted in these clinical scenarios. The majority of therapeutic trials have included the application of triple therapy with proton pump inhibitors or ranitidine bismuth citrate, clarithromycin and either amoxycillin or metronidazol and is to date the treatment of choice. However, recent studies have reported antibiotic resistance which can be one reason for failure of treatment of Helicobacter pylori infection [101-103], and new treatment strategies are therefore Wellcome. Flavonoids, in addition to their gastroprotective activity previously commented, have been also shown to inhibit Helicobacter pylori growth in vitro. In this way, Beil et al. [50]... 

Fig. 11. Eight transient 500 MHz H-NMR spectra of an 11.9 pg (0.027 pmol) sample of the antibiotic clindamycin (7) prepared in 500 pL of CDC13 in a 5 mm NMR tube (top trace) 292 pL in a 4mm tube (middle trace) and 163 pL in a 3 mm tube (bottom trace). All data were acquired using a 500 MHz 5 mm gradient inverse triple resonance Varian Cold-probe . The s/n ratio was measured for each spectrum using a 200 Hz region of representative noise downfield of the anomeric proton resonating at 5.3 ppm. The s/n ratios were 14.4 1, 20.8 1, and 21.5 1 for the 5, 4, and 3mm tubes, respectively.

H. pylori infections are normally treated by a triple therapy course over a week, namely two antibiotics plus an acid inhibitor, for example amoxicillin, clarithromycin and a PPI such as omeprazole. 

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