Trimethylantimony dichloride

The receiver containing the ethereal solution of trimethyl-stibine is kept in ice, and the stopper is replaced with a gas inlet tube connected to a cylinder of chlorine. The inlet tube should extend at least 2 cm. below the level of the liquid in the flask. The mixture is stirred slowly and chlorine is bubbled in until the slurry turns yellowish in color. The precipitate of trimethylantimony dichloride which has formed during the chlorination is removed by filtration on a fritted Buchner funnel and washed several times with ethyl ether. The yield of crude product is 95.9 g. (64.2% of theoretical based upon SbCls). 

The crude product may be recrystallized from w ater. However, trimethylantimony dichloride is only a little more soluble in hot water than it is in cold. A good yield of product of excellent purity may be obtained by removal of most of the water in vacuo by use of a rotatory vacuum evaporator. Yield of purified product 88.4 g. (59.3% of theoretical based upon SbCls). Anal. Calcd. for (CH3)3-SbCla Sb, 51.27 C, 15.17 H, 3.27. Found Sb, 51.39 C, 15.12 H, 3.99. 

---

Trimethylamine, ACl6 Trimethylammonium chloride, AC21 Trlmethylani1inium chloride, AQOO Trimethylantimony dichloride,... 

The steps involved in the synthesis of trimethylantimony dibromide are the same as those for the preparation of trimethylantimony dichloride up to the addition of the chlorine. Instead of a gas inlet tube, an addition funnel is mounted on the flask containing the ice-cold distillate of ethyl ether and trimethylstibine. A solution of 100 g. (0.627 mol) of bromine in 500 ml. of carbon tetrachloride is added dropwise while the reaction mixture is gently stirred. The addition is stopped when the slurry remains yellowish brown. The crude material is filtered with suction on a fritted Buchner funnel and washed several times with... 

Trimethylantimony dichloride, dibromide, and diiodide have been shown to consist of trigonal bipyramidal molecules with the halogens at the apices and the methyl groups in the planar positions. Although melting points have been reported for these compounds from time to time, they are not reproducible because the compounds loose methyl halide upon heating. This reaction is useful for the prepa-... 

Organoantimony (V) dihalides exist in a triangular bipyramidal geometry with the typically bond angles as shown below for trimethylantimony dichloride (1). The two halides reside in the axial positions whereas the organic moieties are present on the equalitorial plane. 

Products from triphenylantimony dichloride and cephalexin show good inhibition of Balb/3T3 cells to 2 ng/mL polymers from triphenylarsenic dibromide and cephalexin exhibit cells to 50 pg/mL and those from trimethylantimony dibromide and cephalexin show good inhibition to 15 pg/mL. The structure for the triphenylantimony dichloride and cephalexin product is given below. 

---