Trimethyl chlorosilane

The reaction of lithiated cumulenic ethers with ethylene oxide, trimethyl-chlorosilane and carbonyl compounds shows the same regiosnecificity as does the alkylation. 

Trimethylsylilmethyl telluride generated in situ from methyllithium and trimethyl-chlorosilane can be used instead of the tellurolate in the latter reaction. ... 

Goethite CO2 SO2 pyridine, acetic acid vapour, CO2, nitric oxide, trimethyl chlorosilane Russell et ah, 1975 Kaneko and Inouye, 1981 Rochester and Topham, 1979 c... 

NH3, pyridine, nitric oxide, CO2, acetic acid, vapour, trimethyl chlorosilane Rochester and Topham, 1979b... 

Trimethylsilyl hydroperoxide preparation bis(trimethylsilyl) peroxide hydrolysis, 801 tetraethylsilane ozonolysis, 810 trimethyl chlorosilane reaction, 776, 777... 

In the reduction of conjugated dienes cis 1,4-addition of trimethyl-chlorosilane to give c -l,4-bis(trimethylsilyl)-2-butene is favored with sodium in THF, lithium naphthalide in THF, and with lithium in diethylether. It appears that the anion radical, which in nonionizing solvents should exist in a cis configuration, leads to the cis 1,4-addition of the silyl groups, whereas the dianions produced by further reduction lead to trans products (140). 

What would happen if the fused silica capillary was coated by trimethyl-chlorosilane ... 

The T2 linker has recently been shown to be a versatile backbone amide anchor. Immobilized disubstituted triazenes were acylated with carboxylic acid anhydrides or chlorides to give amide derivatives. These amides were cleaved under very mild conditions using trimethyl chlorosilane. This sequence thus employs the T2 system as backbone amine linker and was demonstrated in the automated library synthesis of substituted amide derivatives.54... 

The trimethylsilylated ylides (1), easily generated from trimethyl chlorosilane and ylides, react with aldehydes 2 to form vi-nylsilanes 3 (2,3). The vinylphosphonium silanolates 4 are also formed. Compounds 3 are versatile reagents for further reactions (4). The ylide J (with R1 =H) reacts with aldehydes 2 to give the dienes j). The oxidation of with the adduct 6, from triphenyl-phosphite and ozone, gives access to a generaT synthesis of acyl-silanes (trimethylsilylketones) (2). The silylated ylides react to form phosphonium salts 7 with halogen compounds. The salts 7.can be desilylated by fluorine ions. The disubstituted ylides JO Tormed can be converted in statu nascendi with aldehydes V[ into the tris-substituted olefin J2 (2,3). In the case of R3-I, vinyl... 

Cementation consists in the formation of a surface alloy with a less reactive metal. For zinc, alloying can be effected with mercury (amalgamation), copper, silver, nickel.12 The reactivity of a cemented metal can be explained considering that the supporting metal plays only the role of an electron reservoir, the true chemistry is effected by the superficial additional metal. Zinc can also be activated by washing with aqueous ammonium chloride,13 or by reacting the powder with trimethyl-chlorosilane.14 In this latter case, Barbier reactions were effected even at 0°C in short times. The activation mechanism was not determined. 

Industrial chlorination of methyltrichlorosilane and trimethylchlorosi-lane is conducted by a similar technique. It should be borne in mind, however, that the chlorination speed of methyl groups greatly depends on the number of methyl radicals in the original methylchlorosilanes. Trimethyl-chlorosilane is the easiest to chlorinate, methyltrichlorosilane is the hardest. For example, the chlorination speed at the transition from dimethyldi-chlorosilane to trimethylchlorosilane increases 9-fold. 

X-Ray studies of crystals of pyridine complexes with trimethylsilyl bromide and iodide (264) and of N-methylimidazole adducts to trimethyl-chlorosilane (265) were performed. The tetracoordinate silicon structure of these complexes was proved. The distances between the halogen and silicon atoms in pyridine adducts are 4.359 and 4.559 A for bromine and iodine, respectively, which is approximately 2 A greater than the sum of the covalent radii and significantly longer (0.5 A) than the sum of the van der Waals radii. This result is consistent with the ionic structures of the complexes in the solid state. The distance from silicon to nitrogen (1.86 A) is evidently larger than the length of typical Si—N bonds (1.75 A), which... 

As in other preparative methods for organosilicon compounds, the direct synthesis produces a mixture of methylchlorosilanes rather than the single compound shown in equation 3. Besides dimethyl-dichlorosilane, the mixture usually contains silicon tetrachloride, tri-chlorosilane, methyltrichlorosilane, methyldichlorosilane, trimethyl-chlorosilane, and even silicon tetramethyl. Under proper conditions, dimethyldichlorosilane is the principal product. Of the other compounds, methyltrichlorosilane usually is next in abundance this substance finds use in the cross-linked methyl silicone resins, or it can be methylated further by the Grignard method to increase the yield of dimethyldichlorosilane. There is no way of recycling it in the direct process, and so supplemental operations are required for the conversion. The interconversion of this and the other minor products of the direct synthesis, involving the exchange of methyl and chlorine groups as desired, has been a special study in itself.10... 

Only the strong bases HMPT and NMI catalyze the hydrogenation of trimethyl chlorosilane. Both catalysts NMI and P(NEt2)3 form solid adducts with Me3SiCl, but no hydrogenation was observed in the case of P(NEt2)3. 

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