Trigeminal ganglion systems

Two of the sensations associable with trigeminal ganglion systems are the pungent sensation and the astrigent sensation. These sensations are elicitable from much of the oral cavity. 

TK NKxr displays a broad distribution in both peripheral tissues and in the central nervous system (CNS). In both CNS and enteric neurons, NKxr stimulation increase their excitability, whereas in trigeminal ganglion neurons SP has no intrinsic electrophysio-logical effects but is capable to enhance the amplitude of the inward current induced by the stimulation of serotonin 5-HT3 recqrtors. This enhancement dqjends on the activation of PKC via the stimulation of NKX recqrtors. This is an interesting case of receptor cross talk. Other functions of NKxr have been also highlighted. 

Other chemical sensations associated with the trigeminal ganglion include temperature sensations such as the coolness (35) associated with menthol and the heat associated with capsaisin. Oral sensations elicited by chemical solutions also include tactile sensations such as smooth, dry, or powdery, and such disagreeable sensations as pain. Some of these sensations may represent different degrees of activation of a single system or the activation of several separate systems. 

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