Trichothecium

Vanhaelen, M., Vanhaelen, F. R., Geeraerts, J. and Wirtthlin, T. (1979). cis- and i/m.v-Octa-1,5-dicn-3-ol, new attractants to the cheese mite Tyrophagus putrescentiae (Schrank) (Acarina, Acaridae) identified in Trichothecium roseum (Fungi imperfecti). Microbios 23 199-212. 

Nocardia restrictus is capable of oxidizing the conessine derivative 5a-conanin-3/i-ol (220) to both the A4-3-ketone 222 and the A1,4-3-ketone 221, the latter being the major product of the incubation (189). Preliminary screening experiments have demonstrated that Trichothecium rosevan transforms conessine (223), solanocapsine (224), jervine (225), and pseudojervine (226) (42). Transformation of the latter is claimed to produce 20-30% jervine by glycoside hydrolysis, along with an unidentified product that may be further biotransformation product of jervine. Jervine is also metabolized by Polystictus versicolor and Piricularia oryzae, but no products have been identified (42). 

It is not our intention to discuss all the data concerning the trichothecenes that are active against both plants and animals or to name them. They are metabolites of the fungi Acremonium, Cylindrocarpon, Dendrostilbella, Fusarium, Myrothecium, Trichoderma and Trichothecium, but only Cylindrocarpon, Fusarium, Myrothecium, and Trichothecium are considered phytopathogenic. And, as a further note, of 15 evaluated in the etiolated wheat coleoptile bioassay, all were significantly active (p< 0.01) to one degree or another, and the most active were the macrocyclic trichothecenes. Of the latter, verrucarin A and J, and trichoverrin B were highly potent. 

Ahmad, A., Senapati, S., Khan, M.I., Kumar, R., and Sastry, M. 2005. Extra-Zintracellular, biosynthesis of gold nanoparticles by an alkalotolerant fungus, Trichothecium sp. Journal of Biomedical Nanotechnology, 1 47-53. 

Several species of Fusarium infect com, wheat, barley, and rice. Under favorable conditions they elaborate a number of different types of tetracyclic sesquiterpenoid mycotoxins that are composed of the epoxytrichothecene skeleton and an olefinic bond with different side chain substitutions (fig. 9). Based on the presence of a macrocyclic ester or ester-ether bridge between C-4 and C-15, trichothecenes are generally classified as macrocyclic (type C) or nonmacrocyclic (types A and B) (table 5). Other fungal genera producing trichothecenes are Myrothecium, Trichoderma, Trichothecium, Acremonium, Verticimonosporium and Stachybotrys. The term trichothecenes is derived from trichothecin, the first compound isolated in this group [115, 147-153]. 

At one time the microbial introduction of a hydroxy group into the tertiary 17a-position of steroids was considered to have potential importance as a stage in the preparation of adreno-corticosteroids. In this connection, 17a-hydroxylation of 21-hydroxyprogesterone (1) was undertaken with Trichothecium roseum 289 and Cephalotheeium roseum 290. 

The trichothecane group of sesquiterpenoids are now well recognized metabolites from such fungal sources as Trichothecium, Myrothecium, and Fusarium. To date the main interest in this group has centred around isolation, structural... 

Further studies have been made concerning the formation of the mycotoxin trichothecin (47) produced by Trichothecium roseum. Earlier reports of H/ C ratios obtained after feeding [2- H2]- or [5- H2]-MVA (together with [2- C]MVA) that had supported the involvement of the co-metabolite crotocin (50) as an... 

Rhizopus stolonifer, Rhizopus oryzae A. alternata Trichothecium roseum Fusarium moniliforme... 

Cane et a/.92 have re-examined the biosynthesis of trichodiene (127) by incubation of trans,trans[ -3U2,12,13-14C]farnesyl pyrophosphate (156) [3H/14C atom ratio 2 2] with a cell-free extract of Trichothecium roseum. A crystalline derivative of the trans-diol derived from the endocyclic double bond of labelled trichodiene had a... 

J. Favre-Bonvin, J. Bernillon, N. Salin, N. Arpin (1987). Biosynthesis of mycosporines mycosporine glutaminol in Trichothecium roseum. Phytochemistry, 26, 2509-2514. 

Trichothecium roseum produces a pink growth on decaying apples and it was... 

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