2 ,4,5-Trichlorophenol major contaminant

From 1935 to 1978, workers world-wide were exposed during periodic explosions at trichlorophenol production facilities as well as during their daily production activities. Table II illustrates some major industrial accidents which yielded published reports of health effects. Table III lists some major health outcomes reported following exposures to products contaminated with 2,3,7,8-TCDD. The primary dermal effect of exposure is chloracne, a persistent form of acne caused by exposure to a number of chlorinated organic compounds. Chloracne occurred in some exposed persons in all accidents, as well as in children in Seveso (2-4). Chloracne appeared with and without other health effects and persisted in some persons up to 28 years after exposure (5-6). 

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