Trichloroleucine metabolite

The sponge Dysideci herbaceci from the Great Barrier Reef contains the novel metabolite herbacic acid (207) as the major trichloroleucine metabolite [165]. 

MacMillan, J.B. and Molinski, T.F. (2000a) Herbacic acid, a simple prototype of 5,5,5-trichloroleucine metabolites from the sponge Dysidea herbacea. J. Nat. Prod., 63,155-157. 

This new metabolite belongs to the L-series of trichloroleucine peptides and is a rare example of a non-/V-methylated trichloroleucine amino acid (992). Another sample of this sponge from the same locale has yielded the new thiazoles 945 and 946, which are also related to dysidenin (993). The Panamanian Lyngbya majuscula has afforded the new dysidenamide (947), pseudodysidenin (948), and nordysidenin (949), which is the first report of dysidenin-like compounds from a free-living cyanobacterium (994). 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ , ]

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