Trichloro acetyl chloride

PROBABLE FATE photolysis not important except as photooxidation, C-Cl bond can photolyze slowly oxidation tropospheric photooxidation by hydroxyl radicals yields trichloro-acetyl chloride and phosgene, predominant fate, photooxidation half-life in air 16-160 days hydrolysis probably too slow to be important volatilization rapid volatilization is the primary transport process sorption too slow to compete with volatilization biological processes moderate potential for bioaccumulation, possible biodegradation by higher organisms... 

Acetic anhydride Acetyl chloride Alkylaluminums Allyl trichloro silane Aluminum chloride, anhydrous... 

Hethyl-l-cyclopentene Cyclopentene, 1-raethyl- (8,9) (693-89-0) Trlchloroacetyl chloride Acetyl chloride, trichloro- (8,9) (76-02-8)... 

Preparation. Dichloroketene has been generated in situ by dehydrohalogena-tion of dichloroacetyl chloride with trimethylamine (1, 222) and from trichloro-acetyl bromide by dehalogenation with copper-activated zinc (1, 1287). 

Beilstein Handbook Reference) Acetyl chloride, trichloro- BRN 0774120 CCRIS 6764 Diphosgene EINECS 200-926-7 HSDB 6321 NSC 190466 Superpalite Trichloroacetic acid chloride Trichloroxetochloride UN244Z Has been used as a military poison gas. mp = -57° bp = 117.9° d = 1.6202 very soluble in organic solvents reacts with H2O. Sigma-Aldrich Fine Chem. 

Carboxylic acid chlorides from carboxylic acids and 2,2,2-trichloro-l,3,2-benzodioxa-phosph(v)ole 1127 A mixture of the acid (0.02 mole) and the trichloride (0.02 mole) is heated and the acid chloride is then separated by distillation. Yields are acetyl chloride 67% (after 30 min at 100° b.p. 50-51°) benzoyl chloride 81 % (after 60 min at 100° b.p. 82-85°/ll mm) chloroacetyl chloride 77% (after 30 min at 150° b.p. 105-108°). In other cases the reaction mixture can be diluted with ether, poured on ice, and well shaken therewith the aqueous phase should be extracted again with ether, the organic phases then being washed with sodium hydrogen carbonate solution and with water and dried over Na2S04, the ether removed, and the residue distilled. 

Acetyl chloride/aluminum chloride Trichloro- from trifluoro-methyl groups... 

Brigl (76) has obtained (77) a stable 3,4,6-tri-0-acetyl-2-0-(trichloro-acetyl)-/3-D-glucosyl chloride by the action of solid phosphorus pentachlo-ride on /3-D-glucopyranose pentaacetate. This compound yields 1,3,4,6-... 

AlGlg added in small portions to a stirred mixture of a,a,a-trifluoro-3,5-dinitro-toluene and acetyl chloride, heated to 70°, and stirring continued until the mixture nearly solidifies a,a,a-trichloro-3,5-dinitrotoluene. Y 50%. F. e. s. W. T. Smith, Jr., H. H. Ghen, and J. M. Patterson, J. Org. Ghem. 26, 4713 (1961). 

The trichloro compound functions as a halogen carrier and readily loses one of its 4,4-dichloro atoms when mixed with a carboxylic acid for example, it converts acetic acid into acetyl chloride and this provides another good method of converting the trichloride into the chlorocoumarin. 

Preparative Method can be prepared starting from trichloro-silane by treatment with i-PrMgCl, H2O, and acetyl chloride. Alternatively, it can be prepared by the reaction of 1,1,3,3-tetraisopropyldisiloxane with CCI4 in the presence of catalytic PdCl2. This method is also suitable for its in situ preparation. Handling, Storage, and Precautions the liquid is corrosive and insoluble in water. 

One of the best-known carbohydrates of the anhydro class is 1,2-anhydro-3,4,6-tri-O-acetyl-a-D-glucopyranoside, commonly called Brigl s anhydride. It is prepared from p-D-glucopyranoside pentaacetate by reaction with phosphorous pentachloride in carbon tetrachloride to give 3,4,6-tri-0-acetyl-2-0-trichloro-acetyl-P-D-glucopyranosyl chloride from which 1,2-anhydro-tri-O-acetyl-a-D-glucopyranoside is obtained by further treatment with dry ammonia in benzene [63,64] (reaction 4.57). 

Trityl Ethers. Treatment of sucrose with four molar equivalents of chlorotriphenylmethyl chloride (trityl chloride) in pyridine gives, after acetylation and chromatography, 6,1, 6 -tri-O-tritylsucrose [35674-14-7] and 6,6 -di-O-tritylsucrose [35674-15-8] in 50 and 30% yield, respectively (16). Conventional acetylation of 6,1, 6 -tri-O-tritylsucrose, followed by detritylation and concomitant C-4 to C-6 acetyl migration using aqueous acetic acid, yields a pentaacetate, which on chlorination using thionyl chloride in pyridine and deacetylation produces 4,l, 6 -trichloro-4,l, 6 -trideoxygalactosucrose [56038-13-2] (sucralose), alow calorie sweetener (17). 

Acetyl-2-methyl-2,5,6-trichloro-2//-pyran (122 R = Cl, R1 = Me) and 3,4,5,6-tetrachloro-2-trichloromethyl-2//-pyran (144c) eliminated hydrogen chloride to provide 2-methylene derivatives 582a162 and 582b.188,444... 

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