Triazoacetic acid

Hydrazine salts have been prepared by the action of hypochlorites on ammonia1 or urea 2 by the hydrolysis of salts of sulfohydrazimethylene disulfonic acid 3 by the hydrolysis of triazoacetic acid 4 by the reduction of diazoacetic ester 5 by the reduction of nitroguanidine followed by hydrolysis 6 by the reduction of the nitroso derivatives of hexamethylene tetramine 7 by the reduction of nitrates or nitrites with zinc in neutral solution 8 by the action of sodium bisulfite on hyponitrous acid... 

Acetic Acid, Azido Derivative (Axidoacetic Acid or Triazoacetic Acid), N,. CHa. COaH, mw 101.07, N 41.5855. Col hygrosc plates, mp ca 16°, bp 93° at 3 mm, d 1.354 at 33° Detonates violently on heating in a capillary tube expl mildly with evoln of flame on heating on a hot plate. Can be prepd by shaking ethylester of azidoacetic acid with aq 20% KOH soln... 

Diazidoacetic Anhydride, NrHaC.OC.O.CO. CHj.Nj, mw 184.12, N45.65%. Col oil, bp 110° at 0,2 mm. Indexed in CA as Triazoacetic Acid Anhydride. Prepd by shaking an abs ether suspension of the Ag salt of azidoacetic acid with a soln of azidoacetyl-chloride in abs ether... 

Acetic Acid, Diosido Derivative (Asido-acetlc Acid Aside or Triazoacetic Acid),. 

Acetic Acid, Diozido Derivative (Azido-acetic Acid Azide or Triazoacetic Acid),-N,. CH,. CO. N, mw 126.08, N66.66%. 

Hydrazine salts have been prepared by the action of hypochlorites on ammonia (1) or urea (2) by the hydrolysis of salts of sulfohydrazimethylene disiilfonic acid (3) by the hydrolysis of triazoacetic acid (4) by the reduction of diazoacetic ester (5) by the reduction of nitroguanidine followed by hydrolysis (6) by the reduction of the nitroso derivatives of hexamethylene tetramine (7) by the reduction of nitrates or nitrites with zinc in neutral solution (8) by the action of sodium bisulfite on hyponitrous acid followed by reduction (9) by the reduction of K2S03N202 (10) by the action of ammonia on dichlorourea (11) by the reduction of nitrosoparaldimin (12) by the action of copper sulfate on ammonia at high temperatures (13) by the reduction of methylene diisonitrosoamine (14) by the hydrolysis of the addition product of diazoacetic ester and fumaric or cinnamic esters (15). 

Hydrazin—Diamid—HaN.NHa—is known in the form of its hydroxid, corresponding to ammonium hydroxid,in the form of its salts and id numerous organic derivatives. The sulfate is produced by the action of HjSO< upon triazoacetic acid, and the liydroxid by decomposition of the sulfate by caustic soda. The hydroxid is an oily liquid, intensely corrosive, capable of attacking glass. It combines with acids to form weU-deiined salts, and precipitates many metals from solutions of their salts. 

Curtius began work at Kolbe s suggestion on Dessaignes synthesis of hippuric acid (see p. 315) and at Baeyer s suggestion in Munich he used the ethyl ester of glycocoll, which he prepared. By the action of hydrochloric acid and sodium nitrite on this he discovered diazoacetic ester, the first aliphatic diazo-compound. He discovered hydrazine by the action of hot dilute acids on what he supposed was triazoacetic acid C3H3Ne(COOH)3, the sodium salt of which he obtained by the action of concentrated sodium hydroxide on diazoacetic ester.The starting material was later shown to be bisdiazoacetic... 

Salicylic Acid Triazoacetate. See under Acetylsalicylic Acid A87-L Salp eter s aure-Dia zoph osph en yl s aure of Michaelis. See Compound CeH6NjOeP + 3H,0 A246-R... 

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