Trasylol - Aprotinin

Trasylol (Aprotinin). Bayer Healthcare. US Prescribing infonnaticn, December 2003. [Pg.460]

Add RNasin (Promega) and Trasylol (aprotinin solution, Bayer). [Pg.526]

Aprotinin (Trasylol) Dextran 40 (Gentran 40, Rheomacrodex) Reteplase (Retavase)... [Pg.50]

Aprotinin (Trasylol) [Antithrombotic Agent/Protease Inhibitor]... [Pg.79]

Cardiopulmonary bypass, with extracorporeal circulation during cardiac artery bypass graft or heart valve replacement surgery, causes transient hemostatic defects in blood cells and perioperative bleeding. The protease inhibitor aprotinin (Trasylol) inhibits kalhkrein (coagulation phase) and plasmin (hbrinolysis) and protects platelets from mechanical injury. The overall effect after infusion is a decrease in bleeding. [Pg.265]

Aprotinin (Trasylol) shghtly reduces plasma cholinesterase activity and would only be expected to prolong the action of suxamethonium in combination with other factors. However, re-paralysis has been reported when this agent was used after operations during which suxamethonium had been given alone or in combination with normal doses of D-tubocurarine (278). [Pg.3265]

Doenicke A, Gesing H, Knimey 1, Schmidii er St. Influence of aprotinin (Trasylol) on the action of suxamethonium. BrJAnae (1970) 42,948-60. [Pg.118]

Nature has evolved many examples of antagonism at the polypeptide level. A polypeptide (mol. wt. 6512) called aprotinin ( Trasylol ), abundantly present in mammalian tissues, inhibits the hypotensive kinin of the pancreas (kalikrein) as well as the proteolytic action of the enzymes trypsin, chymotrypsin, and plasmin. It has been used with success to treat pancreatitis (Trapnell, 1977). Again, melanostatin and somatostatin polypeptides from the hypothalamus,... [Pg.334]

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