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Transporters genetic variations

Hariri AR, Mattay VS, Tessitore A, Kolachana B, Fera F, Goldman D, Egan MF, Weinberger DR (2002) Serotonin transporter genetic variation and the response of the human amygdala. Science 297 400-403... [Pg.221]

Hahn MK, Blakely RD (2007) The fimctional impact of SLC6 transporter genetic variation. Aimu Rev Pharmacol Toxicol 47 401-441... [Pg.189]

Smeraldi, E., Zanardi, R. et al. (1998). Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine. Mol. Psychiatry, 3(6), 508-11. Wang, S. L., Huang, J. D. et al. (1993). Molecular basis of genetic variation in debrisoquin hydroxylation in Chinese subjects polymorphism in RFLP and DNA sequence of CYP2D6. Clin. Pharmacol. Ther., 53(4), 410-18. [Pg.37]

Backstrom, G., Taipalensuu, J., Melhus, H., et al. (2003) Genetic variation in the ATP-binding Cassette Transporter gene ABCG2 (BCRP) in a Swedish population. Eur. J. Pharm. Sci. 18, 359-364. [Pg.76]

Greenberg, B.D., Tolliver, T.J., Huang, S.J., Li, Q., Bengel, D., and Murphy, D.L. (1999) Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets. Am J Med Genet 88 83-87. [Pg.93]

Frikke-Schmidt R, Nordestgaard BG, Jensen GB, Tybjaerg-Hansen A (2004) Genetic variation in ABC transporter A1 contributes to HDL cholesterol in the general population. J Clin Invest 114 1343-1353... [Pg.545]

Lazar A, Grundemann D, Berkels R, Taubert D, Zimmermann T, Schomig E. Genetic variations of the extraneuronal monoamine transporter EMT (SLC22A3). J Hum Genet 2003 48 226-230. [Pg.139]

David SP, Murthy NV, Rabiner EA, et al. A functional genetic variation of the serotonin (5-HT) transporter affects 5-HT1A receptor binding in humans. J Neurosci 2005 25 2586-2590. [Pg.603]

Several genetic polymorphisms have been identified for the genes encoding the monoamine transporters. A brief review of these genetic variations and possible associations with disease states is presented below and in Table 1. A comprehensive review by Hahn and Blakely examines the impact of genetic variations of the SLC6 gene family (Hahn and Blakely, 2007). [Pg.177]

Serretti A, Artioli P, Lorenzi C, Pirovano A, Tubazio V, Zanardi R. The C(-1019)G polymorphism of the 5-HTlA gene promoter and antidepressant response in mood disorders preliminary findings. Int J Neuropsychopharmacol 2004, 7 453-60. David SP, Murthy NV, Rabiner EA, Munafo MR, Johnstone EC, Jacob R, Walton RT, Grasby PM. A functional genetic variation of the serotonin (5-HT) transporter affects 5-HTlA receptor binding in humans. J. Neurosci. 2005 25 2586-2590. [Pg.2258]

Excessive drug binding (e.g., in tissues or to albumin) Genetic variation of a transporter protein A Question Which of these factors cause the typical age-related reduction of enzyme activity ... [Pg.1899]

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See also in sourсe #XX -- [ Pg.38 ]



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