Antigens transplantation

Proteins are the most abundant and diverse class of antigens to which the immune system can respond. This class includes toxins, allergens, products of infectious organisms, and transplantation antigens. Also included in this class are proteins that are of particular interest to archaeologists, such as blood and tissue proteins, which may be soluble or found on the cell surface, secreted or nonsecreted. 

HLA-D antigens Transplantation antigens bound to liposomes Subunits A and B of cholera toxin... 

Medicare covers immunosuppressives after organ transplants, antigens, blood-dotting factors for hemophiliacs, and dialysis drugs such as erythropoeitin. 

The members of the immunoglobulin superfamily that are encoded in the major histocompatibility complex (MHC) (Fig. 8) constitute a large family which, on the basis of functional criteria, can be divided into two major sets [88—91]. The first consists of antigen-presenting molecules and includes the classical transplantation antigens (class I, see below) and immune response factors (class II). The function of the second is presumably in differentiation, since these molecules (which in the mouse include the Qa and TL antigens [92]) are expressed on specific cell types molecules analogous to this second set V (CD1) are also encoded by a small family... 

Cell surface antigens are probably present on all cells of an organism and may persist in cell cultures for long periods after explantation. For example, mouse L-cells maintained their characteristic transplantation antigens for over 25 years in culture (Sanford et aL, 1958 Defend et al., 1960 Gangal et al, 1966). 

Roser, B., Brown, R.E. Singh, P.B. 1991. Excretion of transplantation antigens as signals of genetic individuality. In Chemical Senses. Volume 3. Genetics of Perception and Communications (Ed. by C.J. Wysocki M.R. Kare), pp 187-209. New York Marcel Dekker. 

Transplantation antigens, hislocompalibiliiy antigens antigens on the surface of nucleated cells, particularly leukocytes and to a lesser extent thrombocytes. A lack of correspondence between T. a. of donor and recipient leads to transplant rejection. To insure optimal compatibility between donor and recipient, the T. a. of both are typed by the histocompatibility test. 

Barry D. Kahan and Ralph A. Reisfeld, Transplantation Antigens Markers of Biological Individuality. 1972... 

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