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Carcinogenesis transplacental

Preconceptual and transplacental carcinogenesis are special types of developmental toxicity and can result when either parent is exposed prior to mating. Both male-mediated and female-mediated effects have been demonstrated in experimental animals for a variety of chemicals and several types of radiation (Anderson, 2000). Transplacental carcinogenesis is recognized in the female, but carcinogenesis mediated through the male germ cells is not as well appreciated or understood. [Pg.97]

Alexandrov VA (1976) Some results and prospects of transplacental carcinogenesis studies. Neoplasma, 23(3) 285-299. [Pg.138]

Donovan PJ (1999) Cell sensitivity to transplacental carcinogenesis by /V-ethyl-W-nitrosourea is greatest in early post-implantation development. Mutat Res, 427(1) 59-63. [Pg.144]

Male-mediated developmental toxicity and transplacental carcinogenesis... [Pg.197]

Tomatis L Mohr U eds (1973) Transplacental carcinogenesis. Lyon, International Agency for Research on Cancer (IARC Scientific Publications No. 4). [Pg.299]

Transplacental carcinogenesis can and does occur in humans and animals. [Pg.773]

On the contrary, transplacental carcinogenesis of many chemicals is well documented in many experimental studies. Moreover, it has been proved as early as in the 1960s that much lower doses are effective for an in utero exposure than for an exposure in adults... [Pg.132]

Berger, M. R., E. Petru, M. Habs, and D. Sch-maehl. 1987. Influence of perinatal nicotine administration on transplacental carcinogenesis... [Pg.232]

Immaturity of immunosurveillance mechanisms, of special concern for the induction of transplacental carcinogenesis... [Pg.116]

Tomatis, L. Mohr, U., Eds. "Transplacental Carcinogenesis" lARC Scientific Publication No. 4 International Agency for Research on Cancer Lyon, 1973. [Pg.212]

The final point - transplacental carcinogenesis - has in a similar manner as the Thalidomide accident not been predicted from animal experiments but was unfortunately first detected in the human population. Diethylstilbestrol, a synthetic female sex hormone, was found to induce adenoma and carcinoma of the vagina in daughters 15 to 20 years after treatment of the mothers for threatened abortion. [Pg.58]

See other pages where Carcinogenesis transplacental is mentioned: [Pg.320]    [Pg.320]    [Pg.98]    [Pg.247]    [Pg.247]    [Pg.169]    [Pg.261]    [Pg.46]    [Pg.122]    [Pg.212]    [Pg.1121]    [Pg.583]    [Pg.772]    [Pg.773]    [Pg.2663]    [Pg.256]    [Pg.47]    [Pg.382]    [Pg.433]    [Pg.433]    [Pg.137]    [Pg.137]    [Pg.309]    [Pg.2181]    [Pg.58]   
See also in sourсe #XX -- [ Pg.320 ]

See also in sourсe #XX -- [ Pg.247 ]

See also in sourсe #XX -- [ Pg.132 ]



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Carcinogenesis

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