Transition metal catalysts Suzuki-Miyaura reaction

Han F-S. Transition-metal-catalyzed Suzuki-Miyaura cross-coupling reactions a remarkable advance from palladium to nickel catalysts. Chem Soc Rev. 2013 42 5270-5298. 

It has been proven that the chiral Pd(II) complexes as transition metal catalysts vs Lewis acid catalysts bring a breakthrough in the frontier of catalytic asymmetric organic synthesis. Here we discussed the key issues based on asymmetric carbon-carbon bond formations anomalous six-membered ring formation, ene-type cyclization leading to five-membered rings, spiro cycliza-tion, alkaloid and quinoline synthesis, Suzuki-Miyaura coupling, and C-H bond activation/C-C bond formation by transition metallic Pd(II) catalysts. On the other hand, the carbonyl-ene reaction, hetero Diels-Alder reaction, and... 

Catalytic hydroboration of alkenes and alkynes can be achieved by the reaction of dialkoxyboranes such as pinacolborane 55 and catecholborane 56 in the presence of transition metal catalysts such as CpjZrHCl, Rh(PPh3)3Cl, or Rh(PPh3)2COCl, (Scheme 28.14). This reaction is of particular significance because it readily provides alkyl/vinylboronates directly in one step for further utility in Suzuki-Miyaura cross-coupling reaction. 

The nature of ligands, such as Boxs, phosphines, and N-heterocyclic carbenes (NHC), bound to a transition metal center usually afiects the selectivities and reaction rates in the organic reactions. Styring et al. described the preparation of a Pd (Il)-salen complex immobilized on Merrifield resin (42). The polymer catalyst facilitated the Suzuki-Miyaura cross-coupling reaction in a continuous-flow system (Scheme 7.32) [130]. The reactor continuously afforded biaryl adducts (43) from aryl... 

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