Transcriptional regulation genomic structure

Figure 7-2. Structure of the cellulose biosynthesis operon bcs in Salmonella typhimurium and Escherichia coli. Arrowheads represent the open reading frames (ORFs). Symbols above the ORFs show overlap of (D) or distance between (A) ORFs in bps. Symbols below the ORFs show insertions (A) or deletions (V), which occur in S. typhimurium LT2 as compared to Escherichia coli K-12. Closed arrow5 just above the ORFs indicate transposon insertions in bcsA and bcsC. The larger arrow indicates the position of the transposon used to study transcriptional regulation of the respective gene. The table summarizes the features of bcs genes using the positioning in the genome of the sequenced LT2 strain. The start codon proposed for bcsC in E. Coli K-12 leads to a shorter ORF (bcsC ).

---