Trans -Piceid

Yitrac X, Bornet A, Yanderlinde R, Vails JM, Richard T, Delaunay J-C, Merillon J-M, Teissedre P-L. 2005. Determination of stilbenes (8-viniferin, trans-astringin, trans-piceid, cis- and trans-resveratrol, e-viniferin) in Brazilian wines. J Agric Food Chem 53 5664-5669. 

Henry C, Vitrac X, Decendit A, Ennamany R, Krisa S, Merillon JM. 2005. Cellular uptake and efflux of trans-piceid and its aglycone traw-resveratrol on the apical membrane of human intestinal Caco-2 cells. J Agric Food Chem 53 798-803. 

Henry-Vitrac C, Desmouliere A, Girard D, Merillon JM, Krisa S. 2006. Transport, deglycosylation, and metabolism of trans-piceid by small intestinal epithelial cells. Eur J Nutr 45 376-382. 

Counet C, Callemien D, Collin S. 2006. Chocolate and cocoa New sources of trans-resveratrol and trans-piceid. Food Chem 98 649-657. 

Among polyphenols, resveratrol and its derivatives are thought to play a special role. Resveratrol occurs naturally in grapes in both cis-and trans-isomers, and in their respective glucosides (cis- and trans-piceids). All forms inhibit the oxidation of low density lipoprotein (LDL) and additional benefits. Resveratrol occurs in most red wines but is undetectable or occurs in negligible amounts in dry white wines (Pour Nikfardjam, 2002). 

Yeh et al. [10] tested chrysophanic acid, emodin (5), physcion (6), emodin-8-0-(3- D-glucoside (7), physcion-8-O-P-Dglucoside (8), and trans-piceid (16) on HL-60 cells to determine their cytotoxic effects. The cells were exposed to known concentrations of the compounds for 72 hours and, using the trypan blue exclusion method, the viable cells were counted. As revealed in Table 2, the results indicate that emodin is the most cytotoxic compound tested. The observed potency is in the order emodin > physcion-8-0- 3-D- glucoside > fraras-piceid > physcion > emodin-8-0- 3-D-glucoside > chysophanic acid. 

Tomato Grape/ overexpression CaMV35S/ StSy Stilbene synthase Resveratrol High trans-resveratrol (48.48 mg kg FW) and trans-piceid (126.58 mg kg FW)/ decrease in rutin (2-fold) and naringenin (2.4-fold) Seedless fruit [67]... 

The green grape skin is also capable of synthesizing phytoalexins in response to an infection (Langcake and Pryce, 1977). These stilbenic derivatives (trans-resveratrol and its glycoside, trans-piceid, dimer e-viniferin, a-viniferin trimer, /S-viniferin tetramer) have fungicidal properties (Figure 10.24). 

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